(S)-Fmoc-3,4-difluoro-β-Homophe-OH

CAS 270063-55-3C25H21F2NO4Chemical Synthesis

(S)-Fmoc-3,4-difluoro-β-Homophe-OH (CAS: 270063-55-3) is a specialised unnatural amino acid derivative with a molecular weight of 437.44 g/mol. Featuring an Fmoc-protected amine and a difluorophenyl side chain, it is primarily utilised in advanced chemical synthesis and peptide chemistry. Its unique structure makes it a valuable building block for the creation of novel peptides and peptidomimetics with potential applications in chemical biology research.

IUPAC: (S)-3-(Fmoc-amino)-4-(3,4-difluorophenyl)butyric acid,Fmoc-3,4-difluoro-L-β-homophenylalanine
Synonyms: (S)-3-(Fmoc-amino)-4-(3,4-difluorophenyl)butyric acidFmoc-3,4-difluoro-L-β-homophenylalanine

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(S)-Fmoc-3,4-difluoro-β-Homophe-OH (C25H21F2NO4) — chemical structure, CAS 270063-55-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Beta-Amino AcidsChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

This compound serves as a key unnatural amino acid building block for incorporating difluorinated phenyl moieties into peptide chains. It enables the synthesis of modified peptides with altered conformational properties and metabolic stability.

Chemical Biology Research

Its incorporation into biomolecules can be explored for studying protein-ligand interactions or developing novel probes. The difluorophenyl group offers unique spectroscopic or binding characteristics.

Drug Discovery and Development

As a non-canonical amino acid, it can be used in the design and synthesis of peptidomimetics and small molecules with potential therapeutic applications. The fluorine atoms can influence pharmacokinetic properties.

Materials Science

Fluorinated organic molecules are of interest in materials science for their unique electronic and hydrophobic properties. This amino acid derivative could be a precursor for specialised polymers or functional materials.

02 /Properties

Molecular weight	437.44
Empirical formula	C25H21F2NO4
Assay	≥98.0%
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

270063-55-3

MDL number

MFCD01861051

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-Fmoc-3,4-difluoro-β-Homophe-OH used for?

(S)-Fmoc-3,4-difluoro-β-Homophe-OH is primarily used in advanced chemical synthesis and peptide chemistry as a building block for creating novel peptides and peptidomimetics. Its applications extend to chemical biology research and potentially drug discovery due to its unnatural amino acid structure.

What is the CAS number and formula for (S)-Fmoc-3,4-difluoro-β-Homophe-OH?

The CAS number is 270063-55-3 and the empirical formula is C25H21F2NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-Fmoc-3,4-difluoro-β-Homophe-OH with an assay of ≥98.0%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.

How should (S)-Fmoc-3,4-difluoro-β-Homophe-OH be handled and stored?

Due to its chemical nature, appropriate personal protective equipment including eyeshields and gloves should be used. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The compound should be stored at 2-8°C.

Is this product a controlled substance?

This product is not listed as a controlled substance.

How is this product shipped internationally?

Tech Serve Solutions is experienced in exporting fine chemicals globally, ensuring compliance with all necessary shipping regulations for research and industrial use.