(S)-Fmoc-2-methyl-β-Homophe-OH
(S)-Fmoc-2-methyl-β-Homophe-OH (CAS: 270062-91-4) is a non-proteinogenic amino acid derivative with the empirical formula C26H25NO4 and a molecular weight of 415.48 g/mol. This compound is valuable in chemical synthesis, particularly for introducing modified amino acid residues into peptides. It finds application in peptide chemistry and chemical biology research, enabling the creation of novel peptide structures with altered properties.
- IUPAC
- (S)-3-(Fmoc-amino)-4-(2-methylphenyl)butyric acid,Fmoc-2-methyl-L-β-homophenylalanine

Peptide Synthesis
Utilised as a building block in solid-phase or solution-phase peptide synthesis to incorporate unnatural amino acid residues. This allows for the modification of peptide backbone structures, influencing conformational stability and biological activity.
Chemical Biology Research
Applied in the design and synthesis of peptides for studying biological processes. The incorporation of this modified amino acid can probe structure-activity relationships or create peptides with unique functionalities.
Drug Discovery and Development
Serves as an intermediate in the synthesis of peptidomimetics or modified peptides investigated for therapeutic potential. Its unique structure can impart desirable pharmacokinetic or pharmacodynamic properties.
Organic Synthesis
A chiral intermediate for the construction of complex organic molecules where a beta-amino acid moiety with specific stereochemistry is required.
| Molecular weight | 415.48 |
|---|---|
| Empirical formula | C26H25NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Fmoc-2-methyl-β-Homophe-OH used for?
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(S)-Fmoc-2-methyl-β-Homophe-OH is used in peptide synthesis, chemical biology research, drug discovery, and general organic synthesis as a chiral building block for introducing unnatural beta-amino acid residues.
What are the CAS number and formula for (S)-Fmoc-2-methyl-β-Homophe-OH?
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The CAS number is 270062-91-4, and the empirical formula is C26H25NO4.
What grade and purity does Tech Serve Solutions supply for (S)-Fmoc-2-methyl-β-Homophe-OH?
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Tech Serve Solutions supplies (S)-Fmoc-2-methyl-β-Homophe-OH with a purity of ≥98.0% (HPLC). This product is typically supplied for research and development purposes and is not intended for pharmaceutical, human, or animal use.
How should (S)-Fmoc-2-methyl-β-Homophe-OH be handled and stored?
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Handle (S)-Fmoc-2-methyl-β-Homophe-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 respirator filter is recommended. Store the compound at 2-8°C to maintain its integrity.
Is (S)-Fmoc-2-methyl-β-Homophe-OH a hazardous substance?
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The compound has a WGK Germany classification of 3, indicating it is hazardous. Appropriate safety precautions as outlined in the safety data sheet must be followed during handling and storage.
How is (S)-Fmoc-2-methyl-β-Homophe-OH packed and shipped?
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Products are carefully packed according to international shipping regulations for chemicals and exported globally by Tech Serve Solutions.
How can I request a sample or quote for (S)-Fmoc-2-methyl-β-Homophe-OH?
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Please contact our sales department through the website or by phone to request a sample or obtain a quotation for (S)-Fmoc-2-methyl-β-Homophe-OH.
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