2,3,4,5,6-Pentafluorobenzylzinc chloride solution
2,3,4,5,6-Pentafluorobenzylzinc chloride solution (CAS: 308796-02-3, C6F5CH2ZnCl, MW: 281.93) is a versatile organozinc halide reagent supplied by Tech Serve Solutions. This solution, typically 0.5 M in THF, is primarily employed in organic synthesis for various coupling reactions and the introduction of the pentafluorobenzyl group into complex molecules. Its reactivity makes it valuable in the development of pharmaceuticals and advanced materials.
- Synonyms
- 5,6-Pentafluorobenzylzinc chloride solutionC6F5CH2ZnCl
Organometallic Synthesis
This reagent serves as a key building block in organometallic chemistry, facilitating carbon-carbon bond formation through reactions like Negishi coupling. It is instrumental in synthesizing complex organic structures.
Pharmaceutical Intermediate Development
The pentafluorobenzyl moiety can be incorporated into drug candidates to modify their pharmacokinetic or pharmacodynamic properties. This compound enables efficient synthesis of such intermediates.
Materials Science
Used in the synthesis of novel materials where the electron-withdrawing nature of the pentafluorophenyl group influences material properties. Applications include functional polymers and electronic materials.
| Molecular weight | 281.93 |
|---|---|
| Linear formula | C6F5CH2ZnCl |
| Boiling point | 65 °C |
| Density | 0.99 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4,5,6-Pentafluorobenzylzinc chloride solution used for?
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This solution is used in organic synthesis, particularly for coupling reactions and the introduction of the pentafluorobenzyl group into molecules. It is valuable in the development of pharmaceuticals and advanced materials.
What is the CAS number and molecular formula for this compound?
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The CAS number is 308796-02-3, and the molecular formula is C6F5CH2ZnCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not represent it as USP, BP, or EP grade. For specific assay details, please consult the Certificate of Analysis.
What are the safety and handling considerations for this chemical?
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This product is flammable (flash point -17 °C) and may form explosive peroxides. It is a skin and eye irritant and may cause respiratory irritation. Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment. Refer to the Safety Data Sheet for comprehensive information.
How is 2,3,4,5,6-Pentafluorobenzylzinc chloride solution packed and shipped?
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This product is shipped under controlled conditions to maintain its integrity. As a flammable liquid, shipping complies with international regulations for UN 2056, Hazard Class 3, Packing Group II. We export globally.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
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