2,3,4,5,6-Pentafluorobenzylzinc bromide solution
2,3,4,5,6-Pentafluorobenzylzinc bromide solution (CAS: 352534-75-9; C6F5CH2ZnBr; MW: 326.38) is a vital organozinc reagent offered by TSS. Supplied as a 0.5 M solution in THF, it functions as a potent nucleophile in organic synthesis. Its primary applications involve the introduction of the pentafluorobenzyl group into organic molecules, facilitating the construction of complex fluorinated compounds essential in pharmaceuticals and materials science.
- Synonyms
- 5,6-Pentafluorobenzylzinc bromide solutionC6F5CH2ZnBr
Fluorinated Compound Synthesis
Utilised as a key building block for introducing the pentafluorobenzyl moiety in the synthesis of complex organic molecules. This is crucial for developing novel pharmaceuticals and advanced materials with tailored properties.
Organometallic Cross-Coupling Reactions
Serves as an organozinc nucleophile in various cross-coupling reactions, enabling the formation of carbon-carbon bonds with diverse electrophilic partners.
Medicinal Chemistry Research
Incorporates the pentafluorobenzyl group into drug candidates to modulate pharmacokinetic and pharmacodynamic properties, influencing lipophilicity and metabolic stability.
| Molecular weight | 326.38 |
|---|---|
| Linear formula | C6F5CH2ZnBr |
| Boiling point | 65 °C |
| Density | 1.018 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | 17 °C / 62.6 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4,5,6-Pentafluorobenzylzinc bromide solution primarily used for?
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This organozinc reagent is primarily used in organic synthesis for introducing the pentafluorobenzyl group into target molecules, particularly in the development of fluorinated pharmaceuticals and materials.
What is the CAS number and chemical formula for 2,3,4,5,6-Pentafluorobenzylzinc bromide solution?
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The CAS number is 352534-75-9 and the linear formula is C6F5CH2ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. The specific assay or purity of the active organozinc species is not detailed beyond its solution concentration. TSS does not represent this product as meeting USP, BP, or EP standards.
What are the main safety hazards associated with this chemical?
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This chemical is highly flammable (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). It may form explosive peroxides and requires careful handling.
How is 2,3,4,5,6-Pentafluorobenzylzinc bromide solution packed, shipped, and exported?
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As a flammable liquid (UN 2056, Class 3, Packing Group II), it is packaged in compliance with international transportation regulations for hazardous materials. TSS is an experienced global exporter.
How can I request a sample or quote for this product?
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To request a sample or a quote, please use the contact form on the Tech Serve Solutions website or contact our sales team directly, providing the product name and CAS number (352534-75-9).
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