2,3,4,5,6-Pentafluorophenylacetic acid
2,3,4,5,6-Pentafluorophenylacetic acid (CAS 653-21-4), with the molecular formula C6F5CH2CO2H and a molecular weight of 226.10 g/mol, is a fluorinated organic compound. It serves as a valuable building block in organic synthesis. This carboxylic acid is primarily utilised in chemical research and for the preparation of more complex fluorinated molecules, contributing to advancements in materials science and medicinal chemistry.
- Synonyms
- 5,6-Pentafluorophenylacetic acidC6F5CH2CO2H
Preparation of 2,3,4,5,6-Pentafluorophenylacetyl Chloride
2,3,4,5,6-Pentafluorophenylacetic acid is a direct precursor for the synthesis of 2,3,4,5,6-pentafluorophenylacetyl chloride. This transformation is crucial for introducing the pentafluorophenylacetyl moiety into various organic structures.
Synthesis of Phenacyl Acetate Derivatives
This compound can be employed in the preparation of substituted phenacyl acetates, such as 4-bromo-phenacyl-2,3,4,5,6-pentafluorophenyl acetate. These derivatives may find use in further synthetic applications or as intermediates.
Fluorinated Building Block
As an aryl fluorinated building block, 2,3,4,5,6-Pentafluorophenylacetic acid offers a versatile platform for incorporating a highly fluorinated aromatic ring into target molecules, enabling the development of novel materials and pharmaceuticals.
| Molecular weight | 226.10 |
|---|---|
| Linear formula | C6F5CH2CO2H |
| Assay | 99% |
| Solubility | 95% ethanol: soluble50 mg/mL, clear, colorless to very faintly yellow |
| Application | 2,3,4,5,6-Pentafluorophenylacetic acid has been used in the preparation of:• 2,3,4,5,6-pentafluorophenylacetyl chloride1• 4-bromo-phenacyl-2,3,4,5,6-pentafluorophenyl acetate2 |
| Melting point | 108-110 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4,5,6-Pentafluorophenylacetic acid used for?
+
2,3,4,5,6-Pentafluorophenylacetic acid is used as a building block in organic synthesis, particularly for preparing derivatives like 2,3,4,5,6-pentafluorophenylacetyl chloride and substituted phenacyl acetates. It is also valuable in chemical research for creating complex fluorinated organic molecules.
What is the CAS number and molecular formula for 2,3,4,5,6-Pentafluorophenylacetic acid?
+
The CAS number is 653-21-4, and the molecular formula is C6F5CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,3,4,5,6-Pentafluorophenylacetic acid with a minimum purity of 99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2,3,4,5,6-Pentafluorophenylacetic acid be handled?
+
Handle with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Ensure good ventilation. It is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is 2,3,4,5,6-Pentafluorophenylacetic acid available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,3,4,5,6-Pentafluorophenylacetic acid.
How can I request a sample or quote for 2,3,4,5,6-Pentafluorophenylacetic acid?
+
Please contact our sales team via the website or by phone to request a sample or obtain a quotation for 2,3,4,5,6-Pentafluorophenylacetic acid.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis