(S)-Fmoc-3-cyano-β-Homophe-OH
(S)-Fmoc-3-cyano-β-Homophe-OH (CAS 270065-87-7) is an unnatural amino acid derivative with the molecular formula C26H22N2O4 and a molecular weight of 426.46. This compound, featuring an Fmoc-protected amine and a cyano-substituted phenyl ring, is valuable in peptide chemistry and chemical synthesis. It serves as a building block for constructing modified peptides and complex organic molecules, contributing to advancements in chemical biology and drug discovery.
- IUPAC
- (S)-3-(Fmoc-amino)-4-(3-cyanophenyl)butyric acid,Fmoc-3-cyano-L-β-homophenylalanine

Peptide Synthesis
Serves as a non-proteinogenic amino acid building block for the synthesis of modified peptides, enabling the incorporation of unique structural and functional properties into peptide chains.
Chemical Synthesis
Utilised as an intermediate in the construction of complex organic molecules and novel chemical entities, particularly where a cyano-substituted phenyl group and a chiral centre are desired.
Chemical Biology Research
Employed in research settings to explore structure-activity relationships and develop new biologically active compounds, contributing to the understanding of molecular interactions.
Unnatural Amino Acid Derivatives
A key component in the synthesis of unnatural amino acids, expanding the scope of amino acid libraries for applications in medicinal chemistry and materials science.
| Molecular weight | 426.46 |
|---|---|
| Empirical formula | C26H22N2O4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Fmoc-3-cyano-β-Homophe-OH used for?
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This compound is primarily used as a building block in peptide synthesis and chemical synthesis. It is also valuable in chemical biology research and for creating unnatural amino acid derivatives.
What is the CAS number and molecular formula?
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The CAS number for (S)-Fmoc-3-cyano-β-Homophe-OH is 270065-87-7, and its molecular formula is C26H22N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Fmoc-3-cyano-β-Homophe-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should (S)-Fmoc-3-cyano-β-Homophe-OH be handled safely?
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When handling this chemical, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound has a WGK Germany classification of 3, indicating a high hazard to water.
How is this product typically shipped or exported?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping methods for (S)-Fmoc-3-cyano-β-Homophe-OH are tailored to ensure product integrity and compliance with international regulations, typically requiring storage at 2-8°C.
How can I request a sample or quote?
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To request a sample or a quote for (S)-Fmoc-3-cyano-β-Homophe-OH, please use the contact form on our website or reach out to our sales team directly.
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