(S)-H8-BINAP

CAS 139139-93-8C44H40P2Chemical Synthesis

(S)-H8-BINAP, identified by CAS number 139139-93-8 and molecular formula C44H40P2, is a crucial chiral diphosphine ligand. With a molecular weight of 630.74 g/mol, it is extensively employed in asymmetric synthesis. Its unique structure facilitates high enantioselectivity in various catalytic transformations, making it invaluable for the synthesis of complex chiral molecules in research and development.

IUPAC: (S)-(−)-2,2′-Bis(diphenylphospino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl,[(1S)-5,5′,6,6′,7,7′,8,8′-octahydro-[1,1′-binaphthalene]-2,2′-diyl]bis[diphenylphosphine]
Synonyms: (S)-(−)-2,2′-Bis(diphenylphospino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl, [(1S)-5,5′,6,6′,7,7′,8,8′-octahydro-[1,1′-binaphthalene]-2,2′-diyl]bis[diphenylphosphine]

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(S)-H8-BINAP (C44H40P2) — chemical structure, CAS 139139-93-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisBINAPsChemical SynthesisChiral CatalystsLigandsand Reagents

01 /Applications

Asymmetric Catalysis

Serves as a key chiral ligand in metal-catalyzed asymmetric reactions, enabling the enantioselective synthesis of chiral compounds. It is particularly recognised for its role in reactions catalysed by ruthenium and rhodium complexes.

Pharmaceutical Intermediate Synthesis

Facilitates the stereoselective synthesis of intermediates crucial for the production of active pharmaceutical ingredients (APIs). Its application contributes to the efficient development of enantiomerically pure drugs.

Advanced Chemical Synthesis

Employed as a privileged ligand in various challenging organic transformations, including asymmetric hydrogenation and carbon-carbon bond formation. It enables the construction of complex molecular architectures with high stereocontrol.

Takasago Ligands and Complexes

This compound is a component within the family of Takasago Ligands, renowned for their efficacy in industrial-scale asymmetric synthesis processes, particularly in the production of pharmaceuticals and fine chemicals.

02 /Properties

Molecular weight	630.74
Empirical formula	C44H40P2
Application	Takasago Ligands and Complexes for Asymmetric Reactions

03 /Identifiers & registry

CAS number

139139-93-8

MDL number

MFCD01630795

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is (S)-H8-BINAP used for?

(S)-H8-BINAP is primarily used as a chiral ligand in asymmetric catalysis, facilitating enantioselective synthesis, particularly in pharmaceutical intermediate production and advanced chemical synthesis.

What is the CAS number and chemical formula for (S)-H8-BINAP?

The CAS number for (S)-H8-BINAP is 139139-93-8, and its empirical formula is C44H40P2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-H8-BINAP at a high purity suitable for research and development. We do not represent this product as USP, BP, or EP grade.

How should (S)-H8-BINAP be handled safely?

(S)-H8-BINAP is classified under Water Hazard Class 3 (WGK 3) in Germany, indicating it is hazardous to the aquatic environment. Handle with appropriate personal protective equipment in a well-ventilated area and avoid release into the environment.

How is (S)-H8-BINAP packed, shipped, and exported?

(S)-H8-BINAP is carefully packaged to ensure stability during transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.