Ethyl 2-acetoxy-2-methylacetoacetate

CAS 25409-39-6CH3COC(O2CCH3)(CH3)CO2C2H5Chemical Synthesis

Ethyl 2-acetoxy-2-methylacetoacetate (CAS: 25409-39-6; Formula: C8H12O5; Molar Mass: 202.20 g/mol) is a specialised organic ester. It serves as a valuable building block in chemical synthesis, particularly within the C8 to C9 molecular weight range. The compound features a reactive keto-ester structure with an acetoxy group, lending itself to various chemical transformations. It is primarily utilised in research and development settings for the preparation of other complex organic molecules and intermediates.

IUPAC: Ethyl 2-acetyllactate acetate

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Ethyl 2-acetoxy-2-methylacetoacetate (CH3COC(O2CCH3)(CH3)CO2C2H5) — chemical structure, CAS 25409-39-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC8 to C9Carbonyl CompoundsChemical SynthesisEsters

01 /Applications

Synthesis of 2-Acetolactate

Ethyl 2-acetoxy-2-methylacetoacetate can be hydrolysed using sodium hydroxide (NaOH) to yield 2-acetolactate, a key intermediate in various biochemical pathways.

Biochemical Research

This compound has been employed in studies involving the isolation and characterisation of novel microorganisms, such as *Geobacillus* sp., for the production of valuable biochemicals like acetoin and 2,3-butanediol.

Organic Synthesis Intermediate

As a versatile building block, Ethyl 2-acetoxy-2-methylacetoacetate is utilised in general organic synthesis for the construction of more complex molecular architectures.

02 /Properties

Molecular weight	202.20
Linear formula	CH3COC(O2CCH3)(CH3)CO2C2H5
Assay	97%
Boiling point	80-84 °C/1 mmHg(lit.)
Density	1.079 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.428(lit.)
Application	Ethyl 2-acetoxy-2-methylacetoacetate was used to prepare 2-acetolactate via hydrolysis with NaOH1. It was also used in isolation and characterization of a novel thermophilic bacterium Geobacillus sp. for the production of acetoin and 2,3-butanediol2.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves
Flash point	104 °C / 219.2 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

25409-39-6

MDL number

MFCD00009127

PubChem substance

24852957

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Ethyl 2-acetoxy-2-methylacetoacetate used for?

It is primarily used as a building block in organic synthesis and for the preparation of compounds such as 2-acetolactate. It has also been used in studies involving the isolation of microorganisms for biochemical production.

What are the CAS number and chemical formula for Ethyl 2-acetoxy-2-methylacetoacetate?

The CAS number is 25409-39-6 and the chemical formula is C8H12O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Ethyl 2-acetoxy-2-methylacetoacetate with a minimum purity of 97%. This product is suitable for general research and technical applications. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.

What are the safety considerations when handling Ethyl 2-acetoxy-2-methylacetoacetate?

When handling this chemical, it is important to wear appropriate personal protective equipment, including eyeshields and gloves. The compound has a flash point of 104 °C (219.2 °F) and is classified under WGK Germany 3, indicating it is hazardous to water.