(S)-Fmoc-3-methyl-β-Homophe-OH
(S)-Fmoc-3-methyl-β-Homophe-OH (CAS 270062-94-7) is a protected unnatural amino acid derivative with the formula C26H25NO4 and a molecular weight of 415.48. It belongs to the class of beta-amino acids and is valuable in chemical synthesis and peptide chemistry. Its Fmoc protecting group facilitates controlled peptide elongation, making it suitable for research in chemical biology and the development of novel peptide structures.
- IUPAC
- (S)-3-(Fmoc-amino)-4-(3-methylphenyl)butyric acid,Fmoc-3-methyl-L-β-homophenylalanine

Peptide Synthesis
This Fmoc-protected beta-amino acid is employed in solid-phase and solution-phase peptide synthesis to incorporate unnatural beta-amino acid residues into peptide chains. It aids in the creation of peptidomimetics with altered conformational properties and enhanced stability.
Chemical Biology Research
It serves as a building block in chemical biology for constructing peptides with non-natural backbones. These modified peptides can be used to probe biological pathways, develop diagnostic tools, or create novel therapeutic agents.
Drug Discovery
The incorporation of unnatural amino acids like (S)-Fmoc-3-methyl-β-Homophe-OH can lead to compounds with improved pharmacokinetic profiles or novel biological activities, supporting early-stage drug discovery efforts.
Organic Synthesis
Beyond peptide chemistry, this compound can be utilized as a chiral intermediate in complex organic synthesis requiring specific stereochemical control and the introduction of modified amino acid functionalities.
| Molecular weight | 415.48 |
|---|---|
| Empirical formula | C26H25NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Fmoc-3-methyl-β-Homophe-OH used for?
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(S)-Fmoc-3-methyl-β-Homophe-OH is primarily used as a protected building block in peptide synthesis, particularly for creating unnatural peptides and peptidomimetics in chemical biology and drug discovery research.
What are the CAS number and molecular formula?
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The CAS number for (S)-Fmoc-3-methyl-β-Homophe-OH is 270062-94-7, and its molecular formula is C26H25NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Fmoc-3-methyl-β-Homophe-OH with an assay of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (S)-Fmoc-3-methyl-β-Homophe-OH be handled and stored?
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Handle (S)-Fmoc-3-methyl-β-Homophe-OH with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Store refrigerated at 2-8°C.
Is this chemical classified as hazardous?
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According to the German WGK classification, this substance is assigned to water hazard class 3 (WGK 3), indicating it is hazardous to aquatic environments.
How is this product exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-Fmoc-3-methyl-β-Homophe-OH, ensuring compliant international shipment.
How can I request a sample or quote?
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To request a sample or quote for (S)-Fmoc-3-methyl-β-Homophe-OH, please contact the Tech Serve Solutions sales team through our website or designated contact channels.
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