(S)-Fmoc-3-(trifluoromethyl)-β-Homophe-OH
(S)-Fmoc-3-(trifluoromethyl)-β-Homophe-OH (CAS: 270065-78-6) is a specialized unnatural amino acid derivative with the molecular formula C26H22F3NO4. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its unique trifluoromethyl substitution offers distinct properties for researchers developing novel peptides and complex organic molecules.
- IUPAC
- (S)-3-(Fmoc-amino)-4-[3-(trifluoromethyl)phenyl]butyric acid,Fmoc-3-(trifluoromethyl)-L-β-homophenylalanine
- Synonyms
- (S)-3-(Fmoc-amino)-4-[3-(trifluoromethyl)phenyl]butyric acidFmoc-3-(trifluoromethyl)-L-β-homophenylalanine

Peptide Synthesis
Incorporated into peptide chains to introduce a trifluoromethyl-substituted beta-homophenylalanine residue, modifying peptide structure and properties.
Chemical Biology Research
Utilised as a tool compound for probing biological systems or developing peptide-based therapeutics with enhanced characteristics.
Organic Synthesis
Acts as a chiral building block for the construction of complex organic molecules and pharmaceutical intermediates where trifluoromethylation is desired.
| Molecular weight | 469.45 |
|---|---|
| Empirical formula | C26H22F3NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Fmoc-3-(trifluoromethyl)-β-Homophe-OH primarily used for?
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This compound is primarily used as a building block in peptide synthesis and chemical biology research, and as a chiral intermediate in organic synthesis.
What is the CAS number and molecular formula for this compound?
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The CAS number is 270065-78-6 and the molecular formula is C26H22F3NO4.
What grade and purity does Tech Serve Solutions supply for (S)-Fmoc-3-(trifluoromethyl)-β-Homophe-OH?
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Tech Serve Solutions supplies this product with an assay of ≥97.0% (HPLC). It is supplied as a research or technical grade material and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this chemical?
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Based on available data, appropriate personal protective equipment including eyeshields and gloves should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is this chemical typically packed, shipped, and exported?
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This chemical is carefully packed according to international shipping regulations to ensure safe transit. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or a quote for (S)-Fmoc-3-(trifluoromethyl)-β-Homophe-OH?
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You can request a sample or a quote by contacting our sales team directly through our website or by calling our customer service department.
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