5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS: 754214-56-7), with the molecular formula C13H17BN2O2 and a molecular weight of 244.10 g/mol, is a heteroaryl boronate ester. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions for the construction of complex molecules. Its structure incorporates a pyrrolo[2,3-b]pyridine core functionalised with a boronate ester, facilitating its use in medicinal chemistry and materials science research.
- IUPAC
- 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine,7-Azaindole-5-boronic acid pinacol ester
- Synonyms
- 5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine7-Azaindole-5-boronic acid pinacol ester
![5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (C13H17BN2O2) — chemical structure, CAS 754214-56-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F754214-56-7.png&w=3840&q=75)
Organic Synthesis Intermediate
Utilised as a key intermediate in Suzuki-Miyaura cross-coupling reactions to introduce the pyrrolo[2,3-b]pyridine moiety into various organic frameworks. Its boronate ester functionality enables regioselective carbon-carbon bond formation.
Medicinal Chemistry Research
A crucial building block for the synthesis of novel drug candidates and biologically active compounds. The pyrrolo[2,3-b]pyridine scaffold is present in various pharmaceuticals, making this reagent valuable for drug discovery programs.
Materials Science
Employed in the development of advanced materials, including organic semiconductors and optoelectronic devices. The unique electronic properties of the heteroaryl system can be leveraged through synthetic modifications facilitated by the boronate ester.
| Molecular weight | 244.10 |
|---|---|
| Empirical formula | C13H17BN2O2 |
| Assay | 97% |
| Storage temperature | −20°C |
| Melting point | 243-248 °C |
Hazard statements
- H302Harmful if swallowed
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine used for?
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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in medicinal chemistry research for the development of new therapeutic agents.
What are the CAS number and molecular formula for this compound?
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The CAS number is 754214-56-7, and the molecular formula is C13H17BN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. It is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine be handled?
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This compound is harmful if swallowed, in contact with skin, or if inhaled (H302 + H312 + H332). Handle with appropriate personal protective equipment, including gloves and eye protection, in a well-ventilated area or fume hood. Avoid dust formation and breathing dust/fume/gas/mist/vapours/spray (P280).
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packaging for safe handling and transport according to international regulations. Please contact us for specific shipping and export inquiries.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales department through the website or by phone. Provide the product name and CAS number (754214-56-7) for efficient processing.
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