1,2,3,5-Tetrafluorobenzene
1,2,3,5-Tetrafluorobenzene (CAS: 2367-82-0), a fluorinated aromatic compound with the molecular formula C6H2F4 and a molecular weight of 150.07 g/mol, serves as a valuable building block in organic synthesis. Its unique fluorination pattern makes it a useful intermediate for introducing fluoroaryl moieties into more complex molecules. This compound is commonly employed in the research and development of novel materials and pharmaceuticals.
- Synonyms
- 5-Tetrafluorobenzene1,2,3,5-TetrafluorobenzeneC6H2F4

Organic Synthesis Intermediate
1,2,3,5-Tetrafluorobenzene is a key intermediate in the synthesis of various organic compounds. Its reactivity allows for further functionalization, making it useful in creating more complex fluorinated molecules for research purposes.
Material Science Research
This compound can be utilised in the development of new materials, particularly where specific electronic or physical properties conferred by fluorination are desired. Its applications may include polymers and specialty chemicals.
Pharmaceutical R&D
As a fluorinated building block, 1,2,3,5-Tetrafluorobenzene is employed in the early stages of drug discovery and development. The incorporation of fluorine atoms can significantly influence a molecule's metabolic stability, lipophilicity, and binding affinity.
| Molecular weight | 150.07 |
|---|---|
| Empirical formula | C6H2F4 |
| Assay | 95% |
| Boiling point | 83 °C(lit.) |
| Density | 1.393 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.404(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 4 °C / 39.2 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,3,5-Tetrafluorobenzene used for?
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1,2,3,5-Tetrafluorobenzene is primarily used as a building block in organic synthesis, particularly in material science research and the development of pharmaceuticals due to its specific fluorination pattern.
What is the CAS number and formula for 1,2,3,5-Tetrafluorobenzene?
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The CAS number for 1,2,3,5-Tetrafluorobenzene is 2367-82-0, and its molecular formula is C6H2F4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,3,5-Tetrafluorobenzene with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1,2,3,5-Tetrafluorobenzene be handled?
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1,2,3,5-Tetrafluorobenzene is a flammable liquid and vapour (H225) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator. Ensure adequate ventilation and keep away from heat, sparks, and open flames.
Is 1,2,3,5-Tetrafluorobenzene packed and shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1,2,3,5-Tetrafluorobenzene, and can arrange for international shipment.
How can I request a quote or sample for 1,2,3,5-Tetrafluorobenzene?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (2367-82-0).
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