1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose
1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose (CAS: 43225-70-3; C13H18O9) is a vital carbohydrate derivative used in intricate chemical synthesis. With a molecular weight of 318.28 g/mol, this compound serves as a key intermediate in the stereoselective synthesis of various complex molecules. Its applications span asymmetric synthesis, the preparation of protected pentofuranosides, and the construction of specific oligosaccharide structures, particularly those found in mycobacterial cell walls.
- IUPAC
- NSC 108078
- Synonyms
- 5-Tetra-O-acetyl-α-D-arabinofuranose
Asymmetric Synthesis of Hydroxyl Acetylpentofuranosides
Utilised as a reactant in the diastereoselective enzymic deacetylation via Candida antarctica B lipase (CAL B)-catalyzed alcoholysis to produce hydroxyl acetylpentofuranosides.
Synthesis of Protected Ribofuranose
Reacts with trimethylaluminum to facilitate the synthesis of 1,2-O-isopropylidene D-ribofuranose, a protected furanose sugar.
Oligosaccharide Synthesis for Mycobacterial Research
Employed in coupling and glycosylation reactions for the synthesis of oligosaccharides mimicking motifs D and E of arabinogalactan, a component of the Mycobacterium tuberculosis cell wall.
| Molecular weight | 318.28 |
|---|---|
| Empirical formula | C13H18O9 |
| Assay | ≥80% |
| Grade | technical grade |
| Boiling point | 140 °C/0.01 mmHg(lit.) |
| Density | 1.31 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4500(lit.) |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Asymmetric synthesis of hydroxyl acetylpentofuranosides via diastereoselective enzymic deacetylation through Candida antarctica B lipase (CAL B)-catalyzed alcoholysis1• Reaction with trimethylaluminum in synthesis of 1,2-O-isopropylidene D-ribofuranose2• Synthesis of oligosaccharides of motifs D and E of arabinogalactan present in Mycobacterium tuberculosis via coupling and glycosylation reactions3 |
Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose primarily used for?
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1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose is used as a reactant in asymmetric synthesis of hydroxyl acetylpentofuranosides, in the reaction with trimethylaluminum for the synthesis of 1,2-O-isopropylidene D-ribofuranose, and in the synthesis of oligosaccharides found in Mycobacterium tuberculosis.
What are the CAS number and molecular formula for this compound?
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The CAS number is 43225-70-3 and the molecular formula is C13H18O9.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product in technical grade with an assay of ≥80%. We do not represent it as USP, BP, or EP grade.
How should 1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose be handled safely?
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Due to the risk of serious eye damage (H318), always wear eye protection such as eyeshields and use a dust mask (N95 type) and gloves when handling. Ensure good ventilation. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical attention.
Does TSS export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or obtain a quotation for 1,2,3,5-Tetra-O-acetyl-α-D-arabinofuranose.
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