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(S)-(−)-3-(Dimethylamino)pyrrolidine

CAS 132883-44-4C6H14N2Chemical Synthesis

(S)-(−)-3-(Dimethylamino)pyrrolidine (CAS: 132883-44-4; Formula: C6H14N2; MW: 114.19) is a chiral pyrrolidine derivative. This valuable building block is primarily utilised in asymmetric synthesis and general chemical synthesis. Its chiral nature makes it instrumental in creating enantiomerically pure compounds, often found in the development of pharmaceuticals and other complex organic molecules. TSS supplies this compound with an assay of 97%.

IUPAC
(3S)-N,N-Dimethyl-3-pyrrolidinamine
Synonyms
(3S)-N,N-Dimethyl-3-pyrrolidinamine
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(S)-(−)-3-(Dimethylamino)pyrrolidine (C6H14N2) — chemical structure, CAS 132883-44-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines
01 /Applications

Asymmetric Synthesis

Serves as a chiral building block for enantioselective synthesis of complex molecules. Its stereochemistry is crucial for controlling the absolute configuration of new chiral centres.

Pharmaceutical Intermediates

Used in the multi-step synthesis of active pharmaceutical ingredients (APIs). The pyrrolidine core is a common motif in many biologically active compounds.

Organic Synthesis Reagent

A versatile reagent in general organic synthesis, facilitating the construction of diverse molecular architectures due to its functional groups.

Chiral Auxiliaries

Can be employed as a chiral auxiliary or ligand in asymmetric catalysis, promoting stereoselective transformations.

02 /Properties
Molecular weight114.19
Empirical formulaC6H14N2
Assay97%
Boiling point160 °C/760 mmHg(lit.)
Density0.899 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.4650(lit.)
Optical activity[α]/D −14±2°, c = 1 in ethanol
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H226Flammable liquid and vapour
  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point51 °C / 123.8 °F
Transport (UN / ADR)UN 1993C 3 / PGIII
Water hazard class (WGK, DE)2
Hazard codes (EU)Xn
Risk statements (R)10-22-37/38-41
Safety statements (S)26-39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
132883-44-4
MDL number
MFCD00191348
PubChem substance
24884218
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-3-(Dimethylamino)pyrrolidine primarily used for?

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(S)-(−)-3-(Dimethylamino)pyrrolidine is primarily used in asymmetric synthesis and general chemical synthesis as a chiral building block for creating enantiomerically pure compounds, often in pharmaceutical development.

What are the CAS number and formula for (S)-(−)-3-(Dimethylamino)pyrrolidine?

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The CAS number for (S)-(−)-3-(Dimethylamino)pyrrolidine is 132883-44-4, and its formula is C6H14N2.

What grade and purity does Tech Serve Solutions supply for (S)-(−)-3-(Dimethylamino)pyrrolidine?

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Tech Serve Solutions supplies (S)-(−)-3-(Dimethylamino)pyrrolidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

What are the key safety hazards associated with (S)-(−)-3-(Dimethylamino)pyrrolidine?

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(S)-(−)-3-(Dimethylamino)pyrrolidine is flammable (H226), harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). It requires careful handling with appropriate personal protective equipment, including eye protection and suitable gloves.

How is (S)-(−)-3-(Dimethylamino)pyrrolidine packed, shipped, and exported by TSS?

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As a global supplier and exporter, TSS ensures secure and compliant packaging for (S)-(−)-3-(Dimethylamino)pyrrolidine, adhering to international shipping regulations for hazardous materials like UN 1993.

How can I request a sample or quote for (S)-(−)-3-(Dimethylamino)pyrrolidine?

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To request a sample or a quote for (S)-(−)-3-(Dimethylamino)pyrrolidine, please contact the TSS sales team through our website or by phone, providing your specific requirements and contact details.

Need (S)-(−)-3-(Dimethylamino)pyrrolidine in a specific grade or volume?