(S)-(−)-2-Methylbutanol
(S)-(−)-2-Methylbutanol (CAS: 1565-80-6), a chiral alcohol with the formula C5H12O and a molecular weight of 88.15 g/mol, is supplied by Tech Serve Solutions. This optically active compound serves as a valuable building block in asymmetric synthesis and chemical manufacturing. Its defined stereochemistry makes it essential for creating specific enantiomers in complex organic synthesis. Offered at a purity of ≥99.5% (sum of enantiomers, GC), it meets stringent requirements for research and industrial applications.
- IUPAC
- (S)-(−)-2-Methyl-1-butanol,Active amyl alcohol
- Synonyms
- (S)-(−)-2-Methyl-1-butanol, Active amyl alcohol

Chiral Building Block in Organic Synthesis
(S)-(−)-2-Methylbutanol is utilised as a chiral precursor in the synthesis of complex organic molecules. Its defined stereochemistry is crucial for building enantiomerically pure compounds used in pharmaceuticals and agrochemicals.
Asymmetric Synthesis Applications
This compound finds application as a chiral auxiliary or reagent in asymmetric synthesis. It enables the control of stereochemistry during the formation of new chiral centres, leading to enantioselective reactions.
Chiral Resolution Reagent
It can be employed in chiral resolution techniques to separate enantiomers of racemic mixtures. By forming diastereomeric derivatives, the separation of individual enantiomers becomes feasible.
| Molecular weight | 88.15 |
|---|---|
| Empirical formula | C5H12O |
| Assay | ≥99.5% (sum of enantiomers, GC) |
| Boiling point | 129-131 °C(lit.) |
| Density | 0.819 g/mL at 20 °C(lit.)0.811 g/mL at 25 °C |
| Refractive index | n/D 1.41n20/D 1.411 |
| Optical activity | [α]20/D −6.3±0.3°, c = 10% in ethanol |


Hazard statements
- H226Flammable liquid and vapour
- H332Harmful if inhaled
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 44 °C / 111.2 °F |
| Transport (UN / ADR) | UN 1105 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20 |
| Safety statements (S) | 24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Methylbutanol primarily used for?
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(S)-(−)-2-Methylbutanol is primarily used as a chiral building block in asymmetric synthesis and for chiral resolution in organic chemistry.
What are the CAS number and formula for (S)-(−)-2-Methylbutanol?
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The CAS number for (S)-(−)-2-Methylbutanol is 1565-80-6, and its formula is C5H12O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-2-Methylbutanol with an assay of ≥99.5% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with (S)-(−)-2-Methylbutanol?
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(S)-(−)-2-Methylbutanol is a flammable liquid and vapour (H226) and harmful if inhaled (H332). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area away from ignition sources.
How is (S)-(−)-2-Methylbutanol packed, shipped, and exported?
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(S)-(−)-2-Methylbutanol is packed in compliance with international regulations for the shipment of hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide.
How can I request a sample or quote for (S)-(−)-2-Methylbutanol?
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To request a sample or quote for (S)-(−)-2-Methylbutanol, please contact our sales team via the website or direct email, providing your requirements.
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