Fmoc-Trp-OPfp
Fmoc-Trp-OPfp (CAS: 86069-87-6) is a protected tryptophan derivative with the empirical formula C32H21F5N2O4 and a molecular weight of 592.51 g/mol. This compound serves as a valuable building block in peptide synthesis, particularly for incorporating tryptophan residues. Its pentafluorophenyl ester moiety facilitates efficient coupling reactions under mild conditions, making it useful in chemical biology and organic synthesis.
- IUPAC
- Fmoc-L-tryptophan pentafluorophenyl ester

Peptide Synthesis
Fmoc-Trp-OPfp is a key reagent for solid-phase and solution-phase peptide synthesis. The Fmoc group provides orthogonal protection, allowing for selective deprotection and coupling during the assembly of complex peptide chains.
Chemical Biology
This compound enables the introduction of tryptophan into peptides and proteins for studies in chemical biology. Such modified biomolecules can be used to investigate protein structure, function, and interactions.
Chemical Synthesis
As an activated amino acid derivative, Fmoc-Trp-OPfp is employed in various organic synthesis strategies where the formation of amide bonds is crucial. Its reactive ester group ensures efficient ligation.
| Molecular weight | 592.51 |
|---|---|
| Empirical formula | C32H21F5N2O4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Trp-OPfp used for?
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Fmoc-Trp-OPfp (CAS: 86069-87-6) is primarily used as a building block in peptide synthesis, chemical biology, and organic synthesis for introducing Fmoc-protected tryptophan residues.
What are the CAS number and empirical formula for Fmoc-Trp-OPfp?
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The CAS number for Fmoc-Trp-OPfp is 86069-87-6, and its empirical formula is C32H21F5N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Trp-OPfp with an assay of ≥98.0%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Trp-OPfp be handled and stored?
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Handle Fmoc-Trp-OPfp with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Fmoc-Trp-OPfp a controlled substance?
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The provided data does not indicate that Fmoc-Trp-OPfp is a controlled substance.
How are Tech Serve Solutions' chemicals shipped?
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Tech Serve Solutions exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary shipping and handling regulations.
How can I request a sample or quote for Fmoc-Trp-OPfp?
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To request a sample or a quote for Fmoc-Trp-OPfp, please contact our sales team through the website or by phone.
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