Fmoc-D-Tic-OH
Fmoc-D-Tic-OH (CAS: 130309-33-0) is a chiral unnatural amino acid derivative with the molecular formula C25H21NO4 and a molecular weight of 399.44 g/mol. It features the Fmoc protecting group and is derived from D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid. This compound is primarily utilised in peptide synthesis and chemical biology research, serving as a building block for complex peptide structures and modified biomolecules.
- IUPAC
- (R)-N-Fmoc-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Peptide Synthesis
Fmoc-D-Tic-OH is employed as a protected unnatural amino acid in solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Its incorporation allows for the construction of peptides with specific structural constraints and novel biological activities.
Chemical Biology
This derivative serves as a valuable tool in chemical biology for developing peptidomimetics and probes. It enables researchers to investigate protein-protein interactions and explore structure-activity relationships in biological systems.
Drug Discovery
As a non-proteinogenic amino acid, Fmoc-D-Tic-OH can be integrated into peptide-based drug candidates to enhance metabolic stability, bioavailability, or receptor binding affinity.
| Molecular weight | 399.44 |
|---|---|
| Empirical formula | C25H21NO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −25.0±2°, c = 0.6% in methanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Tic-OH used for?
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Fmoc-D-Tic-OH is used in peptide synthesis and chemical biology research as a protected unnatural amino acid building block for creating complex peptides and peptidomimetics.
What is the CAS number and molecular formula for Fmoc-D-Tic-OH?
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The CAS number for Fmoc-D-Tic-OH is 130309-33-0, and its molecular formula is C25H21NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-D-Tic-OH?
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Tech Serve Solutions supplies Fmoc-D-Tic-OH with a purity of ≥98.0% determined by TLC. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should Fmoc-D-Tic-OH be handled and stored?
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Handle Fmoc-D-Tic-OH with appropriate personal protective equipment, including eyeshields and gloves. It should be stored at 2-8°C. Consult the safety data sheet for detailed handling information.
Is Fmoc-D-Tic-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-Tic-OH is a controlled substance.
How is Fmoc-D-Tic-OH shipped and exported?
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Tech Serve Solutions, a specialist global supplier and exporter, ships and exports Fmoc-D-Tic-OH under appropriate conditions for chemical compounds. Please contact us for specific export documentation and shipping details.
How can I request a sample or quote for Fmoc-D-Tic-OH?
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To request a sample or a quotation for Fmoc-D-Tic-OH, please contact our sales team through the website or by phone.
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