Lomerizine dihydrochloride
Lomerizine dihydrochloride (CAS: 101477-54-7) is a chemical compound with the formula C27H30F2N2O3·2HCl and a molecular weight of 541.46 g/mol. This white to tan powder is primarily utilised as a research chemical. Its properties as a calcium channel modulator make it a valuable tool in cell biology and neuroscience research, particularly for investigating cellular signaling pathways and ion channel function.
- IUPAC
- 1-[Bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride

Calcium Channel Modulation Research
Lomerizine dihydrochloride acts as a modulator of calcium channels. This property is leveraged in scientific research to study cellular responses, signal transduction pathways, and the physiological roles of ion channels in various biological systems.
Neuroscience and Cell Signaling Studies
This compound is employed in neuroscience to investigate neuronal function and cell signaling mechanisms. Its ability to interact with ion channels makes it a useful reagent for understanding the complex processes occurring within the nervous system.
Cell Biology Investigations
As a bioactive small molecule, Lomerizine dihydrochloride is utilized in cell biology research to probe cellular functions and mechanisms. It aids in understanding cellular processes related to ion transport and membrane potential.
| Molecular weight | 541.46 |
|---|---|
| Empirical formula | C27H30F2N2O3·2HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥30 mg/mL |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lomerizine dihydrochloride used for?
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Lomerizine dihydrochloride is used in scientific research as a calcium channel modulator, particularly in studies related to cell biology, neuroscience, and cellular signaling. It is a research chemical and not intended for human or animal use.
What are the CAS number and formula for Lomerizine dihydrochloride?
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The CAS number for Lomerizine dihydrochloride is 101477-54-7. Its molecular formula is C27H30F2N2O3·2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lomerizine dihydrochloride with a purity of ≥98% (HPLC). This product is supplied for research and laboratory use and is not represented as USP, EP, BP, or pharmacopoeia grade.
What are the safety considerations when handling Lomerizine dihydrochloride?
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Lomerizine dihydrochloride is classified with GHS07 and GHS09 symbols, carrying a 'Warning' signal word. It has hazard statements H302 (Harmful if swallowed) and H410 (Very toxic to aquatic life with long-lasting effects). Appropriate personal protective equipment should be worn, and it should be handled with care to avoid ingestion and environmental release.
How is Lomerizine dihydrochloride packed, shipped, and exported?
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Lomerizine dihydrochloride is typically supplied as a powder. Tech Serve Solutions, as a global supplier and exporter, handles packaging and shipping in accordance with international regulations for chemical transport, ensuring safe and compliant delivery worldwide.
How can I request a quote or sample for Lomerizine dihydrochloride?
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To request a quote or a sample of Lomerizine dihydrochloride, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry and specifications.
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