Lornoxicam

CAS 70374-39-9C13H10ClN3O4S2Cell Biology

Lornoxicam (CAS: 70374-39-9), a potent oxicam derivative with the molecular formula C13H10ClN3O4S2 and a molecular weight of 371.82, is recognized for its significant role as a cyclooxygenase (COX) inhibitor. This compound functions within the arachidonic acid cascade, influencing cellular processes. Its applications span research in cell biology, cell signaling, and neuroscience, particularly as an enzyme inhibitor. Lornoxicam is supplied as a faint yellow to dark yellow powder.

IUPAC: 6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide,Chlortenoxicam,Ro 13-9297,TS 110
Synonyms: 6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxideChlortenoxicamRo 13-9297TS 110

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Lornoxicam (C13H10ClN3O4S2) — chemical structure, CAS 70374-39-9; Life Science, fine chemical supplied by Tech Serve Solutions

Arachidonic Acid CascadeCell BiologyCyclooxygenaseEnzyme Inhibitors

01 /Applications

Cyclooxygenase (COX) Inhibition Studies

Lornoxicam serves as a valuable tool for researchers investigating the mechanisms of cyclooxygenase enzymes. Its inhibitory action is crucial for understanding inflammatory pathways and pain perception at the cellular level.

Cellular Signaling Research

As a modulator of the arachidonic acid cascade, Lornoxicam is employed in studies focusing on cellular signaling pathways. It helps researchers elucidate the complex interplay of lipid mediators in various biological processes.

Neuroscience and Pain Research

This compound is utilised in neuroscience research to explore the role of COX enzymes in neuronal function and pain signaling. Its application aids in understanding the biochemical basis of neurological conditions.

Enzyme Inhibitor Research

Lornoxicam is a key research chemical for studies involving enzyme inhibition. Its specific interaction with COX enzymes makes it an important reagent for evaluating drug targets and developing new therapeutic agents.

02 /Properties

Molecular weight	371.82
Empirical formula	C13H10ClN3O4S2
Assay	≥98% (HPLC)
Form	powder
Colour	faint yellow to dark yellow
Solubility	DMSO: >5 mg/mL (warmed)
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash thoroughly after handling
P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T+
Risk statements (R)	28
Safety statements (S)	28-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

70374-39-9

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Lornoxicam used for?

Lornoxicam is primarily used in scientific research as a cyclooxygenase (COX) inhibitor for studies in cell biology, cell signaling, neuroscience, and related fields. It is a tool for investigating inflammatory pathways and enzyme mechanisms.

What are the CAS number and formula for Lornoxicam?

The CAS number for Lornoxicam is 70374-39-9, and its molecular formula is C13H10ClN3O4S2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Lornoxicam with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Lornoxicam be handled and stored?

Lornoxicam is classified as highly toxic if swallowed (H300) and requires careful handling. It should be stored at -20°C. Always refer to the Safety Data Sheet for comprehensive safety and handling instructions.

Is Lornoxicam a controlled substance?

The provided data does not indicate that Lornoxicam is a scheduled or controlled substance.

How is Lornoxicam packed and exported?

Lornoxicam is typically supplied as a powder and packaged according to international shipping regulations for hazardous materials (UN 2811, 6.1, PGII). Tech Serve Solutions is a global supplier and exporter.