Rauwolscine hydrochloride
Rauwolscine hydrochloride (CAS: 6211-32-1), with the molecular formula C21H26N2O3 · HCl and a molecular weight of 390.90 g/mol, is a white to off-white powder. This compound is recognised for its biological activity, particularly within the adrenoceptor antagonist class. It finds application in scientific research for investigating cellular signaling pathways, neurotransmission, and related neurobiological processes, serving as a valuable tool in cell biology and neuroscience studies.
- IUPAC
- α-Yohimbine hydrochloride,17α-Hydroxy-20α-yohimban-16 β-carboxylic acid methyl ester hydrochloride
- Synonyms
- 17α-Hydroxy-20α-yohimban-16β-carboxylic acid methyl ester hydrochlorideα-Yohimbine hydrochloride
Neuroscience Research
Rauwolscine hydrochloride is utilised in neuroscience research to investigate the function of adrenergic receptors and their role in neurotransmission. Its properties as an antagonist make it useful for probing receptor-mediated pathways in cellular and animal models.
Cell Biology Studies
In cell biology, this compound serves as a bioactive small molecule to study cell signaling mechanisms. Researchers employ it to modulate specific cellular responses influenced by adrenergic signaling, contributing to a deeper understanding of cellular processes.
Pharmacological Tool
As an antagonist, rauwolscine hydrochloride is a valuable pharmacological tool for in vitro and in vivo studies. It aids in characterising the physiological effects of alpha-2 adrenergic receptor blockade and related systems.
| Molecular weight | 390.90 |
|---|---|
| Empirical formula | C21H26N2O3 · HCl |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: soluble |
| Optical activity | [α]25/D +52.13°, c = 1 in H2O |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152), HTR1A(3350) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Rauwolscine hydrochloride used for?
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Rauwolscine hydrochloride is primarily used in scientific research, particularly in neuroscience and cell biology, for investigating adrenergic receptor function, cell signaling pathways, and neurotransmission. It acts as an alpha-2 adrenergic receptor antagonist.
What are the CAS number and formula for Rauwolscine hydrochloride?
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The CAS number for Rauwolscine hydrochloride is 6211-32-1, and its molecular formula is C21H26N2O3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Rauwolscine hydrochloride as a research-grade chemical, typically a white to off-white powder. Specific purity assays are detailed on the product's Certificate of Analysis. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
How should Rauwolscine hydrochloride be handled safely?
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Rauwolscine hydrochloride is classified as Danger, with hazards including acute toxicity via oral, dermal, and inhalation routes (H301, H311, H331). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, is essential. Handle only in a well-ventilated area and avoid exposure.
How is Rauwolscine hydrochloride shipped and exported?
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Rauwolscine hydrochloride is shipped and exported in compliance with international regulations for hazardous materials. It is UN 1544, Class 6.1, Packing Group II, requiring specific packaging and documentation for transport.
How can I request a quote or sample of Rauwolscine hydrochloride?
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To request a quote or sample of Rauwolscine hydrochloride, please contact our sales team through the website or by phone. Provide your details and the product's CAS number (6211-32-1) for prompt service.
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