Ramatroban
Ramatroban (CAS: 116649-85-5), a synthetic compound with the molecular formula C21H21FN2O4S and a molecular weight of 416.47 g/mol, is a research chemical. It is primarily recognised for its role as an antagonist of thromboxane A2 receptors and its application in scientific research concerning cellular signalling and the arachidonic acid cascade. Ramatroban is supplied as a white solid.
- IUPAC
- (+)-(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid,BAY u3405
- Synonyms
- (+)-(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid,BAY u3405
Pharmacological Research
Ramatroban serves as a valuable tool in research settings investigating the mechanisms of thromboxane A2 receptor antagonism. It aids in understanding cellular responses related to blood clotting and vascular function.
Cell Biology Studies
This compound is utilised in cell biology to explore signalling pathways, particularly those involving lipids and the arachidonic acid cascade. Its activity contributes to understanding cell communication and response mechanisms.
Drug Discovery and Development
As an approved therapeutic/drug candidate, Ramatroban is employed in preclinical studies and drug discovery programs aimed at developing new treatments for conditions influenced by thromboxane A2.
| Molecular weight | 416.47 |
|---|---|
| Empirical formula | C21H21FN2O4S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: ≥40 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ramatroban used for?
+
Ramatroban is used in pharmacological research, cell biology studies, and drug discovery, particularly for investigating thromboxane A2 receptor antagonism and related cellular signalling pathways.
What is the CAS number and formula for Ramatroban?
+
The CAS number for Ramatroban is 116649-85-5, and its empirical formula is C21H21FN2O4S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Ramatroban with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should Ramatroban be handled and stored?
+
Ramatroban is classified as a warning substance (GHS07) and can cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Store at 2-8°C.
Is Ramatroban a controlled substance?
+
The provided data does not indicate that Ramatroban is a controlled substance.
How is Ramatroban packed, shipped, and exported?
+
Ramatroban is supplied as a white solid. As a global supplier and exporter, Tech Serve Solutions adheres to all necessary regulations for packing, shipping, and exporting chemical compounds.
How can I request a sample or quote for Ramatroban?
+
Please contact our customer service team to request a sample or a quote for Ramatroban. Our team is available to assist with your specific requirements.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis