Methanesulfonyl fluoride
Methanesulfonyl fluoride (CAS 558-25-8), with the chemical formula CH3SO2F and a molar mass of 98.10 g/mol, is a specialised organic compound. It functions as a valuable building block in chemical synthesis, particularly within the realm of fluorinated organic chemistry. Its reactivity makes it a useful reagent for introducing the mesyl group in various organic transformations.

Organic Synthesis Reagent
Methanesulfonyl fluoride serves as a key intermediate and reagent in the synthesis of complex organic molecules. It is frequently employed to introduce the methanesulfonyl group, a vital moiety in numerous chemical structures.
Fluorinated Building Block
As a fluorinated building block, this compound is integral to the development of novel fluorinated organic materials and pharmaceuticals. Its structure allows for the incorporation of fluorine atoms, which can significantly alter a molecule's properties.
Research and Development
It is used in academic and industrial research laboratories for exploring new synthetic pathways and developing innovative chemical entities. Its specific reactivity profile is of interest for various chemical transformations.
| Molecular weight | 98.10 |
|---|---|
| Linear formula | CH3SO2F |
| Assay | 98% |
| Boiling point | 123-124 °C(lit.) |
| Density | 1.427 g/mL at 25 °C(lit.) |


Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3389 8(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 23-28-34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methanesulfonyl fluoride used for?
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Methanesulfonyl fluoride is primarily used as a building block in organic synthesis and as a reagent for introducing the methanesulfonyl group in the creation of more complex organic molecules, particularly those containing fluorine.
What are the CAS number and formula for Methanesulfonyl fluoride?
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The CAS number for Methanesulfonyl fluoride is 558-25-8, and its chemical formula is CH3SO2F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methanesulfonyl fluoride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Methanesulfonyl fluoride be handled safely?
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Methanesulfonyl fluoride is a dangerous substance requiring extreme caution. It is labelled with GHS05 and GHS06 symbols, with the signal word 'Danger'. It carries hazard statements H300 (Fatal if swallowed), H314 (Causes severe skin burns and eye damage), and H330 (Fatal if inhaled). Appropriate personal protective equipment, including full-face respirators, chemical-resistant gloves, and eye protection, is essential. Handling should occur in a well-ventilated area or fume hood, strictly following all safety protocols.
Is Methanesulfonyl fluoride a controlled substance?
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The provided data does not indicate that Methanesulfonyl fluoride (CAS 558-25-8) is a controlled substance.
How is Methanesulfonyl fluoride packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and shipping details for Methanesulfonyl fluoride are available upon request, adhering to all international transport regulations for hazardous materials.
How can I request a quote or sample for Methanesulfonyl fluoride?
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To request a quote or a sample of Methanesulfonyl fluoride, please contact our sales team through the designated channels on the Tech Serve Solutions website.
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