Methanesulfonyl bromide
Methanesulfonyl bromide (CAS 41138-92-5), with the molecular formula CH3BrO2S and a molecular weight of 159.00 g/mol, is a chemical compound supplied by Tech Serve Solutions. It serves as a valuable reagent in various chemical syntheses. Its primary applications are within organic synthesis, particularly in reactions requiring the introduction of the mesyl group. This compound is known for its reactivity and is handled with appropriate safety precautions.
- IUPAC
- Mesyl bromide

Organic Synthesis Reagent
Methanesulfonyl bromide is employed as a mesylating agent in organic synthesis. It facilitates the conversion of alcohols to mesylates, which are excellent leaving groups for subsequent nucleophilic substitution reactions.
Intermediate in Pharmaceutical Synthesis
This compound can be used as an intermediate in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs). Its reactivity allows for the formation of specific carbon-sulfur bonds.
Protecting and Derivatizing Agent
In certain synthetic strategies, methanesulfonyl bromide can function as a protecting or derivatizing reagent, aiding in the selective modification of functional groups within a molecule.
| Molecular weight | 159.00 |
|---|---|
| Empirical formula | CH3BrO2S |
| Assay | ≥98.0% |
| Density | 1.954 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.510 |


Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3390 8(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/28-35 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methanesulfonyl bromide used for?
+
Methanesulfonyl bromide (CAS 41138-92-5) is primarily used as a mesylating agent in organic synthesis and as an intermediate in the production of complex organic molecules.
What are the CAS number and formula for Methanesulfonyl bromide?
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The CAS number for Methanesulfonyl bromide is 41138-92-5, and its empirical formula is CH3BrO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methanesulfonyl bromide with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
How should Methanesulfonyl bromide be handled safely?
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Methanesulfonyl bromide is a Danger material (GHS05, GHS06) and is acutely toxic if swallowed or inhaled, and causes severe skin burns and eye damage (H300-H314-H330). Handle with extreme care using full protective equipment, including face shields, chemical-resistant gloves, and appropriate respiratory protection (type ABEK respirator filter).
Is Methanesulfonyl bromide a controlled substance?
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The provided data does not indicate that Methanesulfonyl bromide is a controlled substance.
How is Methanesulfonyl bromide packed and shipped?
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Methanesulfonyl bromide is shipped as UN 3390, Class 8(6.1), Packing Group I. Specific packaging details can be provided upon request.
How can I request a sample or quote for Methanesulfonyl bromide?
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To request a sample or a quote for Methanesulfonyl bromide, please contact our sales team through the website or by phone.
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