Methanesulfonic anhydride
Methanesulfonic anhydride (CAS 7143-01-3), with the linear formula (CH3SO2)2O and a molecular weight of 174.20 g/mol, is a potent dehydrating and sulfonating agent. This reactive compound is primarily utilised in organic synthesis as a building block and reagent. Its strong electrophilic nature makes it valuable for various chemical transformations, particularly in the formation of sulfonic acid derivatives and other sulfur-containing organic compounds. Methanesulfonic anhydride requires careful handling due to its reactivity.

Sulfonating Agent
Methanesulfonic anhydride serves as a powerful sulfonating agent in organic synthesis. It facilitates the introduction of the methanesulfonyl group onto various organic substrates, enabling the synthesis of diverse sulfur-containing compounds.
Dehydrating Agent
Due to its strong affinity for water, this anhydride acts as an effective dehydrating agent in specific chemical reactions. It can be employed to remove water molecules, driving equilibrium towards product formation in condensation reactions.
Building Block in Organic Synthesis
As an organic building block, methanesulfonic anhydride is a versatile precursor for creating more complex molecules. It is frequently used in the development of pharmaceutical intermediates and fine chemicals.
| Molecular weight | 174.20 |
|---|---|
| Linear formula | (CH3SO2)2O |
| Assay | ≥96.0% (T) |
| Boiling point | 125 °C/4 mmHg(lit.) |
| Vapour density | 3.3 (vs air) |
| Melting point | 64-67 °C(lit.)65-70 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-35 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methanesulfonic anhydride used for?
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Methanesulfonic anhydride (CAS 7143-01-3) is used as a sulfonating agent, a dehydrating agent, and a versatile building block in organic synthesis for creating various sulfur-containing organic compounds, including pharmaceutical intermediates.
What is the CAS number and formula for Methanesulfonic anhydride?
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The CAS number for Methanesulfonic anhydride is 7143-01-3, and its linear formula is (CH3SO2)2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methanesulfonic anhydride with an assay of ≥96.0% (T). We do not represent this product as USP, BP, or EP grade.
How should Methanesulfonic anhydride be handled safely?
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Methanesulfonic anhydride is a corrosive substance that reacts violently with water. It necessitates the use of appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection. Handle in a well-ventilated area and avoid contact with moisture. Always consult the Safety Data Sheet (SDS) before use.
Is Methanesulfonic anhydride a controlled substance?
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The provided data does not indicate that Methanesulfonic anhydride is a controlled substance.
How is Methanesulfonic anhydride packed and exported?
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Methanesulfonic anhydride is packed and shipped according to international regulations for hazardous materials (UN 3261, Class 8, PG II). Tech Serve Solutions is experienced in exporting such chemicals globally.
How can I request a quote or sample?
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To request a quote or a sample of Methanesulfonic anhydride, please contact our sales team through the website or by phone, providing your details and requirements.
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