Lumefantrine
Lumefantrine (CAS: 82186-77-4), a synthetic antimalarial drug with the chemical formula C30H32Cl3NO, is a key component in combination therapies. It functions by inhibiting the polymerisation of toxic haem metabolites into non-toxic hemozoin, thereby disrupting parasite growth and replication. Its efficacy makes it a vital agent in the management of malaria, particularly in regions where resistance to other antimalarials is prevalent. Tech Serve Solutions supplies Lumefantrine for research and development purposes.
- IUPAC
- (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-?-[(dibutylamino)methyl]-9H-fluorene-4-methanol,Benflumetol,CPG-56695
Antimalarial Research
Lumefantrine is utilised in studies investigating novel antimalarial drug combinations and mechanisms of action against Plasmodium parasites. Its role in inhibiting haem detoxification is a critical area of research.
Drug Discovery and Development
As a well-established antimalarial, Lumefantrine serves as a reference compound in the development of new therapeutic agents targeting malaria. Its pharmacological profile is extensively studied.
Biochemical Research
This compound is employed in biochemical assays to understand its interactions within the parasite and its metabolic pathways. Research may focus on its impact on parasite membranes and enzymes.
| Molecular weight | 528.94 |
|---|---|
| Empirical formula | C30H32Cl3NO |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: ≥20 mg/mL |
| Storage temperature | room temp |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lumefantrine used for?
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Lumefantrine is primarily used in combination therapy for the treatment of malaria. It works by preventing the parasite from detoxifying a harmful substance called heme.
What is the CAS number and chemical formula for Lumefantrine?
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The CAS number for Lumefantrine is 82186-77-4, and its chemical formula is C30H32Cl3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lumefantrine with an assay of ≥98% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should Lumefantrine be handled?
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Lumefantrine is classified under WGK Germany 3, indicating a hazard to water. Handle with appropriate personal protective equipment in a well-ventilated area. Avoid release into the environment.
How is Lumefantrine packed and shipped?
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Lumefantrine is typically supplied as a yellow powder and stored at room temperature. We ensure secure packaging for domestic and international export to maintain product integrity.
How can I request a quote or sample for Lumefantrine?
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To request a quote or a sample of Lumefantrine, please contact our sales team through our website or by phone, providing your specific requirements.
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