Lomeguatrib
Lomeguatrib (CAS 192441-08-0), a purine derivative with the molecular formula C10H8BrN5OS and a molecular weight of 326.17 g/mol, is supplied as a white to beige powder. This compound is of significant interest in biochemical research, particularly within the fields of apoptosis, cell cycle regulation, and DNA metabolism. Its structure suggests potential roles in modulating cellular signaling pathways, making it a valuable tool for investigators studying these complex biological processes.
- IUPAC
- 2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purine,O6-(4-bromothenyl)guanine
- Synonyms
- 2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purineO6-(4-bromothenyl)guanine
Apoptosis and Cell Cycle Research
Lomeguatrib serves as a research chemical for studies investigating the intricate mechanisms of programmed cell death (apoptosis) and the regulation of the cell cycle. Its specific interactions within cellular pathways can help elucidate novel targets for therapeutic intervention.
DNA Metabolism and Repair Studies
Researchers utilise Lomeguatrib to explore pathways related to DNA metabolism and repair. Understanding how this compound influences these fundamental processes can provide insights into genomic stability and disease pathogenesis.
Cell Signaling Investigations
The compound is employed in research to probe cellular signaling cascades, particularly those relevant to neuroscience and cell biology. Its application aids in deciphering complex signal transduction networks.
Drug Metabolism Research
Lomeguatrib can be used in studies related to drug and xenobiotic metabolism, contributing to a better understanding of how biological systems process foreign compounds and the implications for drug efficacy and toxicity.
| Molecular weight | 326.17 |
|---|---|
| Empirical formula | C10H8BrN5OS |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble10 mg/mL, clear |
| Storage temperature | room temp |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lomeguatrib used for?
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Lomeguatrib is used in scientific research for studies related to apoptosis, cell cycle regulation, DNA metabolism and repair, and cellular signaling pathways.
What is the CAS number and molecular formula for Lomeguatrib?
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The CAS number for Lomeguatrib is 192441-08-0, and its molecular formula is C10H8BrN5OS.
What grade and purity does Tech Serve Solutions supply for Lomeguatrib?
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Tech Serve Solutions supplies Lomeguatrib with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated. It is suitable for research and laboratory use.
What are the safety considerations when handling Lomeguatrib?
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Lomeguatrib is classified with the GHS07 symbol and a 'Warning' signal word, carrying the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area. Avoid ingestion, inhalation, and contact with skin and eyes. Consult the Safety Data Sheet (SDS) for comprehensive handling guidelines.
How is Lomeguatrib typically supplied and exported?
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Lomeguatrib is supplied as a powder, typically stored at room temperature. As a global supplier, Tech Serve Solutions handles the export of this chemical, adhering to all relevant regulations for international shipment.
How can I request a sample or a quote for Lomeguatrib?
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To request a sample or obtain a quotation for Lomeguatrib, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
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