(1R,2R)-1-Amino-2-benzyloxycyclopentane
(1R,2R)-1-Amino-2-benzyloxycyclopentane (CAS: 181657-56-7) is a chiral organic compound with the molecular formula C12H17NO and a molecular weight of 191.27 g/mol. This valuable building block is primarily utilised in asymmetric synthesis and chemical research. Its structure, featuring a protected amine and alcohol on a cyclopentane ring, makes it a versatile intermediate for constructing complex chiral molecules.
- IUPAC
- (1R)-trans-2-(Phenylmethoxy)cyclopentanamine,(1R,2R)-trans-2-Benzyloxy-cyclopentylamine
- Synonyms
- (1R)-trans-2-(Phenylmethoxy)cyclopentanamine(1R,2R)-trans-2-Benzyloxy-cyclopentylamine

Asymmetric Synthesis
Serves as a crucial chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its defined stereochemistry is essential for creating enantiomerically pure target compounds.
Pharmaceutical Intermediate
This compound acts as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its chiral nature is vital for developing enantiomerically pure drugs with specific pharmacological activities.
Organic Synthesis
Utilised as a versatile reagent in general organic synthesis for introducing specific functional groups and chiral centres. It facilitates the creation of novel molecular architectures.
| Molecular weight | 191.27 |
|---|---|
| Empirical formula | C12H17NO |
| Assay | ≥98.5% (GC)99% |
| Optical purity | enantiomeric excess: ≥98.5% |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-1-Amino-2-benzyloxycyclopentane used for?
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(1R,2R)-1-Amino-2-benzyloxycyclopentane is used as a chiral building block in asymmetric synthesis, a pharmaceutical intermediate, and a versatile reagent in organic synthesis for constructing complex chiral molecules.
What are the CAS number and formula for this compound?
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The CAS number for (1R,2R)-1-Amino-2-benzyloxycyclopentane is 181657-56-7, and its molecular formula is C12H17NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2R)-1-Amino-2-benzyloxycyclopentane with an assay of ≥98.5% (GC) and 99%, with an enantiomeric excess of ≥98.5%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for (1R,2R)-1-Amino-2-benzyloxycyclopentane?
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This compound is classified as Danger, with hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, is essential during handling.
How is (1R,2R)-1-Amino-2-benzyloxycyclopentane packed, shipped, and exported?
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(1R,2R)-1-Amino-2-benzyloxycyclopentane is shipped internationally by Tech Serve Solutions in compliance with transport regulations, specifically UN 2735, Class 8, Packing Group II. Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or a sample of (1R,2R)-1-Amino-2-benzyloxycyclopentane, please contact the Tech Serve Solutions sales team through our website or by phone.
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