(1R,2R)-N,N′-Dihydroxy-N,N′-bis(3,3,3-triphenylpropionyl)-1,2-cyclohexanediamine
(1R,2R)-N,N′-Dihydroxy-N,N′-bis(3,3,3-triphenylpropionyl)-1,2-cyclohexanediamine (CAS 860036-29-9) is a chiral ligand with the molecular formula C48H46N2O4 and a molecular weight of 714.89 g/mol. This compound serves as a crucial component in asymmetric synthesis, specifically in vanadium-catalysed asymmetric epoxidation reactions of allylic alcohols. Its precise stereochemistry makes it valuable for creating enantiomerically pure compounds in chemical synthesis.
- IUPAC
- (1R,2R)-N,N′-Dihydroxy-N,N′-bis(triphenylpropionyl)-cyclohexane-1,2-diamine,(R)-CBHA-TPP,N,N′-(1R,2R)-1,2-cyclohexanediylbis[N-hydroxy-β,β-diphenylbenzenepropanamide]
- Synonyms
- N′-bis(3,3,3-triphenylpropionyl)-1,2-cyclohexanediamine,860036-29-9, C48H46N2O4,(1R,2R)-N,N′-Dihydroxy-N,N′-bis(triphenylpropionyl)-cyclohexane-1,2-diamine,(R)-CBHA-TPP,N,N′-(1R,2R)-1,2-cyclohexanediylbis[N-hydroxy-β,β-diphenylbenzenepropanamide]
Asymmetric Epoxidation
This compound functions as a chiral ligand in conjunction with vanadium for the asymmetric epoxidation of allylic alcohols. This application is vital for stereoselective synthesis, producing specific enantiomers with high purity.
Chiral Catalyst Component
As a ligand, it plays a key role in the formation of chiral catalytic systems. Its structure is designed to induce asymmetry during catalytic reactions, particularly useful in fine chemical and pharmaceutical intermediate synthesis.
Ligand in Metal-Catalysed Reactions
It is employed as a ligand in various metal-catalysed transformations where stereochemical control is paramount. The complex formed with metals like vanadium facilitates enantioselective bond formation.
| Molecular weight | 714.89 |
|---|---|
| Empirical formula | C48H46N2O4 |
| Assay | 95% |
| Optical activity | [α]22/D +22.0±5°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Application | Ligand used with vanadium for asymmetric epoxidation of allylic alcohols1,2 |
| Melting point | 217-221 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-N,N′-Dihydroxy-N,N′-bis(3,3,3-triphenylpropionyl)-1,2-cyclohexanediamine used for?
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This compound is primarily used as a chiral ligand in vanadium-catalysed asymmetric epoxidation of allylic alcohols, contributing to stereoselective synthesis.
What is the CAS number and formula for this chemical?
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The CAS number is 860036-29-9, and the empirical formula (Hill notation) is C48H46N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of 95%. We do not represent this product as USP, BP, or EP grade; it is intended for research and chemical synthesis applications.
What are the safety considerations when handling this compound?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection such as a type N95 (US) or type P1 (EN143) respirator filter. Please consult the Safety Data Sheet for full details.
How is this product shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents. This product is carefully packed and exported in compliance with international shipping regulations.
How can I request a sample or a quote for this chemical?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales department directly, providing the product name and CAS number.
What is the melting point of this compound?
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The melting point is reported to be between 217-221 °C.
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