(1R,2R)-(−)-trans-1-Amino-2-indanol

CAS 163061-73-2C9H11NOChemical Synthesis

(1R,2R)-(−)-trans-1-Amino-2-indanol (CAS: 163061-73-2) is a chiral amino alcohol with a molecular weight of 149.19 g/mol. This compound is a valuable building block in asymmetric synthesis, frequently employed in the development of stereoselective reactions and the preparation of complex organic molecules. Its specific stereochemistry makes it essential for creating enantiomerically pure pharmaceuticals and fine chemicals. Available at 97% assay, it serves as a key intermediate in advanced chemical research and development.

Synonyms: C9H11NO(1R,2R)-(-)-1-Amino-2-indanol(1R,2R)-trans-1-Aminoindan-2-ol

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(1R,2R)-(−)-trans-1-Amino-2-indanol (C9H11NO) — chemical structure, CAS 163061-73-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

As a chiral auxiliary, (1R,2R)-(−)-trans-1-Amino-2-indanol can be temporarily incorporated into a molecule to direct the stereochemical outcome of a reaction, leading to enantiomerically enriched products. It is particularly useful in asymmetric alkylations, reductions, and cycloadditions.

Ligand Development for Asymmetric Catalysis

This amino indanol serves as a precursor for synthesizing chiral ligands. These ligands can then coordinate with transition metals to form catalysts capable of promoting highly enantioselective transformations, critical in pharmaceutical manufacturing.

Building Block for Pharmaceutical Intermediates

Its defined stereochemistry makes it a sought-after starting material for the synthesis of chiral pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It enables the construction of complex molecular architectures with precise spatial arrangements.

Resolution Agent

In certain cases, chiral amino alcohols like this one can be used as resolving agents to separate racemic mixtures into their individual enantiomers, facilitating the production of single-enantiomer drugs.

02 /Properties

Molecular weight	149.19
Empirical formula	C9H11NO
Assay	97%
Optical activity	[α]/D -23.0°, c = 1 in ethanol
Melting point	142-146 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

163061-73-2

MDL number

MFCD08275447

PubChem substance

24884630

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1R,2R)-(−)-trans-1-Amino-2-indanol used for?

This compound is primarily used as a chiral building block in asymmetric synthesis and catalysis, and as an intermediate in the production of pharmaceuticals and fine chemicals.

What is the CAS number and molecular formula for (1R,2R)-(−)-trans-1-Amino-2-indanol?

The CAS number is 163061-73-2, and its molecular formula is C9H11NO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (1R,2R)-(−)-trans-1-Amino-2-indanol with an assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety considerations for handling (1R,2R)-(−)-trans-1-Amino-2-indanol?

This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation.

How is (1R,2R)-(−)-trans-1-Amino-2-indanol packed, shipped, and exported?

Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant transportation and safety regulations to ensure safe delivery.

How can I request a sample or quote for (1R,2R)-(−)-trans-1-Amino-2-indanol?

You can request a sample or quote by contacting our sales team through the website or by calling us directly. Please provide the product name and CAS number (163061-73-2) in your request.