Fmoc-D-Val-OH
Fmoc-D-Val-OH (CAS: 84624-17-9), also known as N-(9-Fluorenylmethoxycarbonyl)-D-valine, is a protected amino acid derivative with the chemical formula C20H21NO4 and a molecular weight of 339.39 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research. Its Fmoc protecting group allows for controlled deprotection under mild basic conditions, facilitating sequential amino acid coupling in solid-phase peptide synthesis. Supplied by Tech Serve Solutions with an assay of ≥98.0%, it is stored at 2-8°C.
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)-D-valine,Fmoc-D-valine
- Synonyms
- N-(9-Fluorenylmethoxycarbonyl)-D-valine,Fmoc-D-valine
Peptide Synthesis
Fmoc-D-Val-OH is a crucial building block in solid-phase peptide synthesis (SPPS). The N-terminal Fmoc group enables orthogonal protection strategies, allowing for the controlled assembly of peptide chains.
Chemical Biology
This derivative finds application in chemical biology for the synthesis of modified peptides, peptidomimetics, and probes. It allows for the incorporation of D-amino acids into peptide structures, influencing their biological activity and stability.
Organic Synthesis
As a chiral building block, Fmoc-D-Val-OH is employed in various organic synthesis pathways. Its defined stereochemistry is valuable for constructing complex molecules where specific spatial arrangements are required.
| Molecular weight | 339.39 |
|---|---|
| Empirical formula | C20H21NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Melting point | 143-144 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Val-OH used for?
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Fmoc-D-Val-OH is primarily used in peptide synthesis and chemical biology for the construction of peptide chains and modified peptides, particularly those incorporating D-amino acids.
What is the CAS number and chemical formula for Fmoc-D-Val-OH?
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The CAS number is 84624-17-9 and the chemical formula is C20H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Val-OH with an assay of ≥98.0% by HPLC. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for Fmoc-D-Val-OH?
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Handling Fmoc-D-Val-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is Fmoc-D-Val-OH stored and shipped?
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Fmoc-D-Val-OH should be stored at 2-8°C. Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging and documentation for international shipment.
How can I request a quote or sample for Fmoc-D-Val-OH?
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To request a quote or sample for Fmoc-D-Val-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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