Fmoc-D-allyl-Gly-OH
Fmoc-D-allyl-Gly-OH (CAS: 170642-28-1) is an unnatural amino acid derivative with the empirical formula C20H19NO4 and a molecular weight of 337.37 g/mol. This compound serves as a valuable building block in peptide synthesis and chemical biology research. Its unique structure, featuring an allylic side chain, allows for diverse chemical modifications and the incorporation of non-natural functionalities into peptide sequences, enabling advanced research in drug discovery and material science.
- IUPAC
- (R)-2-(Fmoc-amino)-4-pentenoic acid,Fmoc-D-2-allylglycine
- Synonyms
- (R)-2-(Fmoc-amino)-4-pentenoic acidFmoc-D-2-allylglycine
Peptide Synthesis
Fmoc-D-allyl-Gly-OH is utilized as a protected unnatural amino acid in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with modified side chains, offering novel properties for biochemical research and therapeutic development.
Chemical Biology Research
This compound is employed in chemical biology to introduce allylglycine residues into biomolecules. The allyl group can be subsequently functionalized through various click chemistry or cross-coupling reactions, facilitating the study of protein interactions and the development of novel molecular probes.
Drug Discovery
As a non-proteinogenic amino acid derivative, Fmoc-D-allyl-Gly-OH aids in the design and synthesis of peptidomimetics and novel drug candidates. Its unique structure can enhance metabolic stability and receptor binding affinity, contributing to the development of new pharmaceutical agents.
Organic Synthesis
Beyond peptide chemistry, Fmoc-D-allyl-Gly-OH can be used in general organic synthesis as a chiral building block. The allylic functionality offers a versatile handle for further synthetic transformations, enabling access to complex molecular architectures.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C20H19NO4 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-allyl-Gly-OH used for?
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Fmoc-D-allyl-Gly-OH is primarily used as a building block in peptide synthesis and chemical biology research. It allows for the incorporation of unnatural amino acid residues with an allylic side chain into peptides, enabling the development of novel peptidomimetics, molecular probes, and modified biomolecules for drug discovery and advanced materials.
What are the CAS number and empirical formula for Fmoc-D-allyl-Gly-OH?
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The CAS number for Fmoc-D-allyl-Gly-OH is 170642-28-1, and its empirical formula is C20H19NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-D-allyl-Gly-OH?
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Tech Serve Solutions supplies Fmoc-D-allyl-Gly-OH with a purity of ≥96.0% (HPLC). This is a research-grade material and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-D-allyl-Gly-OH be handled and stored?
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Handle Fmoc-D-allyl-Gly-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Store the chemical at 2-8°C to maintain its integrity.
Is Fmoc-D-allyl-Gly-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-allyl-Gly-OH is a controlled substance.
How is Fmoc-D-allyl-Gly-OH packed, shipped, and exported?
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Fmoc-D-allyl-Gly-OH is carefully packed and prepared for shipment by Tech Serve Solutions, adhering to all necessary regulations for domestic and international export of fine chemicals.
How can I request a sample or quote for Fmoc-D-allyl-Gly-OH?
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To request a sample or a quote for Fmoc-D-allyl-Gly-OH, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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