Fmoc-D-Tyr(tBu)-OH
Fmoc-D-Tyr(tBu)-OH (CAS: 118488-18-9) is a protected derivative of the non-proteinogenic amino acid D-tyrosine. With the empirical formula C28H29NO5 and a molecular weight of 459.53 g/mol, it features an Fmoc protecting group on the amine and a tert-butyl group on the phenolic hydroxyl. This compound is primarily utilised in solid-phase peptide synthesis and in the development of novel peptide-based therapeutics and chemical biology research.
- IUPAC
- Fmoc-O-tert-butyl-D-tyrosine
- Synonyms
- Fmoc-O-tert-butyl-D-tyrosine
Solid-Phase Peptide Synthesis
Fmoc-D-Tyr(tBu)-OH is a crucial building block in the Fmoc/tBu solid-phase peptide synthesis strategy. The tert-butyl group protects the tyrosine phenol during synthesis, while the Fmoc group allows for facile deprotection and coupling cycles.
Peptidomimetics and Drug Discovery
This D-amino acid derivative enables the incorporation of D-tyrosine into peptides, potentially enhancing their stability against enzymatic degradation and influencing their conformational properties, which is valuable in peptidomimetic design and drug discovery.
Chemical Biology Research
Its unique structure makes Fmoc-D-Tyr(tBu)-OH useful for creating modified peptides for probing biological systems, developing diagnostic tools, or engineering novel biomaterials.
| Molecular weight | 459.53 |
|---|---|
| Empirical formula | C28H29NO5 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Tyr(tBu)-OH used for?
+
Fmoc-D-Tyr(tBu)-OH is primarily used as a protected amino acid building block in solid-phase peptide synthesis, particularly within the Fmoc/tBu strategy, and for research in chemical biology and peptidomimetics.
What are the CAS number and chemical formula for Fmoc-D-Tyr(tBu)-OH?
+
The CAS number is 118488-18-9, and the empirical formula is C28H29NO5.
What grade and purity does Tech Serve Solutions supply for Fmoc-D-Tyr(tBu)-OH?
+
Tech Serve Solutions supplies Fmoc-D-Tyr(tBu)-OH with an assay of ≥98.0% (HPLC). We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should Fmoc-D-Tyr(tBu)-OH be handled and stored safely?
+
When handling, use appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator. It should be stored at 2-8°C. Refer to the safety data sheet for comprehensive handling information. It is classified under WGK Germany 3.
How is Fmoc-D-Tyr(tBu)-OH packed and shipped?
+
Fmoc-D-Tyr(tBu)-OH is carefully packed for stable transport and is available for export globally by Tech Serve Solutions.
How can I request a sample or obtain a quote for Fmoc-D-Tyr(tBu)-OH?
+
To request a sample or obtain a quote, please contact the Tech Serve Solutions sales team through our website or by direct inquiry, providing your contact details and the product CAS number 118488-18-9.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis