Fmoc-D-Trp(Boc)-OH
Fmoc-D-Trp(Boc)-OH (CAS: 163619-04-3) is a protected D-Tryptophan derivative with the molecular formula C31H30N2O6 and a molecular weight of 526.58 g/mol. It features Fmoc protection on the alpha-amino group and Boc protection on the indole nitrogen. This compound is primarily utilised in solid-phase peptide synthesis and the construction of modified peptides, where controlled deprotection steps are crucial for building complex peptide chains.
- IUPAC
- Nα-Fmoc-N(in)-Boc-D-tryptophan
- Synonyms
- Nα-Fmoc-N(in)-Boc-D-tryptophan
Peptide Synthesis
Used as a building block in solid-phase peptide synthesis (SPPS) for incorporating a protected D-Tryptophan residue into peptide sequences. The orthogonal protecting groups allow for selective deprotection during synthesis.
Chemical Biology Research
Facilitates the synthesis of novel peptides for biological studies, including those investigating protein-protein interactions or enzyme activity. The protected D-isomer can introduce specific conformational constraints.
Drug Discovery
Serves as an intermediate in the synthesis of peptide-based drug candidates. The incorporation of modified amino acids like Fmoc-D-Trp(Boc)-OH can enhance peptide stability and pharmacokinetic properties.
Custom Peptide Manufacturing
Essential reagent for custom peptide synthesis services, enabling the creation of peptides with specific sequences and modifications for research and development purposes.
| Molecular weight | 526.58 |
|---|---|
| Empirical formula | C31H30N2O6 |
| Assay | ≥95.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Trp(Boc)-OH used for?
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Fmoc-D-Trp(Boc)-OH is used as a protected building block in solid-phase peptide synthesis and for the construction of modified peptides in chemical biology and drug discovery research.
What are the CAS number and formula for Fmoc-D-Trp(Boc)-OH?
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The CAS number for Fmoc-D-Trp(Boc)-OH is 163619-04-3, and its empirical formula is C31H30N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Trp(Boc)-OH with an assay of ≥95.0% by HPLC. This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-D-Trp(Boc)-OH be handled and stored?
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Handle Fmoc-D-Trp(Boc)-OH with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the chemical at 2-8°C.
Is Fmoc-D-Trp(Boc)-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-Trp(Boc)-OH is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing for international shipment of chemicals like Fmoc-D-Trp(Boc)-OH, adhering to all relevant regulations.
How can I request a quote or sample?
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To request a quote or sample of Fmoc-D-Trp(Boc)-OH, please contact our sales team through the details provided on the Tech Serve Solutions website.
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