Fmoc-D-β-Homophe-OH
Fmoc-D-β-Homophe-OH (CAS: 209252-16-4) is a synthetic unnatural amino acid derivative with the empirical formula C25H23NO4 and a molecular weight of 401.45 g/mol. This compound is a key building block in peptide chemistry and chemical synthesis, particularly for researchers working with modified peptides and peptidomimetics. Its structure incorporates the Fmoc protecting group, facilitating controlled peptide chain elongation in solid-phase or solution-phase synthesis. It is supplied by TSS with an assay of ≥96%.
- IUPAC
- (R)-3-(Fmoc-amino)-4-phenylbutyric acid,Fmoc-D-β-homophenylalanine
- Synonyms
- (R)-3-(Fmoc-amino)-4-phenylbutyric acidFmoc-D-β-homophenylalanine
Peptide Synthesis
Fmoc-D-β-Homophe-OH serves as a crucial unnatural amino acid building block in the synthesis of modified peptides. Its incorporation allows for the creation of peptides with altered structures and potentially novel biological activities.
Chemical Biology Research
This compound is employed in chemical biology to investigate structure-activity relationships in peptides. It enables the study of how the introduction of a beta-homophenylalanine residue impacts peptide conformation and function.
Drug Discovery and Development
As an unnatural amino acid derivative, Fmoc-D-β-Homophe-OH can be used in the development of peptidomimetics and novel therapeutic agents. Its unique structure may offer improved stability or binding properties compared to natural amino acids.
Organic Synthesis Intermediate
Beyond peptide chemistry, this compound can function as an intermediate in complex organic synthesis pathways. The Fmoc protecting group and the chiral beta-amino acid structure offer versatile synthetic handles.
| Molecular weight | 401.45 |
|---|---|
| Empirical formula | C25H23NO4 |
| Assay | ≥96% |
| Optical activity | [α]/D 26.0±3.0°, c = 1 in methanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-β-Homophe-OH used for?
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Fmoc-D-β-Homophe-OH is primarily used as a building block in peptide synthesis, chemical biology, and organic synthesis, particularly for creating modified peptides and peptidomimetics.
What is the CAS number and empirical formula for Fmoc-D-β-Homophe-OH?
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The CAS number for Fmoc-D-β-Homophe-OH is 209252-16-4, and its empirical formula is C25H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-β-Homophe-OH with an assay of ≥96%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for Fmoc-D-β-Homophe-OH?
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Users should wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection. The compound is classified with WGK Germany rating 3, indicating a high hazard to water.
How is Fmoc-D-β-Homophe-OH shipped and stored?
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This product is typically stored at 2-8°C. For shipping, it is packaged to maintain its integrity and stability during transit.
How can I request a sample or quote for Fmoc-D-β-Homophe-OH?
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To request a sample or a quotation, please contact our sales department through the TSS website or by phone, providing the product name and CAS number.
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