5-Pyrimidineboronic acid pinacol ester
5-Pyrimidineboronic acid pinacol ester (CAS: 321724-19-0) is a heterocyclic organoboron compound with the molecular formula C10H15BN2O2 and a molecular weight of 206.05 g/mol. This stable boronate ester serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. It is frequently employed in the development of novel pharmaceutical intermediates and complex organic molecules.
- IUPAC
- 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Suzuki-Miyaura Coupling Reagent
5-Pyrimidineboronic acid pinacol ester is a key reagent in Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of carbon-carbon bonds by coupling with aryl or vinyl halides and pseudohalides.
Pharmaceutical Intermediate Synthesis
This compound is utilised in the synthesis of complex heterocyclic structures relevant to medicinal chemistry. Its pyrimidine core is a common feature in many biologically active molecules and drug candidates.
Organic Synthesis Building Block
As a functionalised boronate ester, it offers a versatile handle for introducing the pyrimidine moiety into various organic frameworks. It is integral in constructing advanced materials and fine chemicals.
| Molecular weight | 206.05 |
|---|---|
| Empirical formula | C10H15BN2O2 |
| Assay | 97% |
| Melting point | 67-71 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Pyrimidineboronic acid pinacol ester used for?
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5-Pyrimidineboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in the development of pharmaceutical intermediates and complex organic molecules.
What is the CAS number and molecular formula for 5-Pyrimidineboronic acid pinacol ester?
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The CAS number is 321724-19-0 and the molecular formula is C10H15BN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Pyrimidineboronic acid pinacol ester with a minimum assay of 97%. This product is not represented as USP, BP, EP or other pharmacopoeia grades; it is suitable for research and technical applications.
What are the safety and handling requirements for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet for comprehensive handling information.
How is 5-Pyrimidineboronic acid pinacol ester packed and shipped?
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Tech Serve Solutions professionally packs and ships this chemical globally, adhering to all relevant regulations for safe transport of laboratory reagents and fine chemicals.
How can I request a quote or sample for 5-Pyrimidineboronic acid pinacol ester?
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To request a quote or sample, please use the contact form on our website or contact our sales team directly. We will respond promptly.
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