(R)-3-Amino-5-hexynoic acid hydrochloride
(R)-3-Amino-5-hexynoic acid hydrochloride (CAS: 332064-87-6), with the molecular formula C6H9NO2 · HCl and a molecular weight of 163.60, is a valuable chiral building block. This compound features both an alkyne and an amino acid moiety, making it highly versatile for chemical synthesis and conjugation chemistry. It serves as a key intermediate in the development of novel molecules and is frequently employed in research settings for drug discovery and peptide synthesis.

Chiral Synthesis
Utilised as a chiral building block in asymmetric synthesis to create enantiomerically pure compounds. Its unique structure allows for stereoselective reactions.
Peptide Chemistry
Incorporated into peptide chains as an unnatural amino acid derivative. This enables the modification of peptide properties for research purposes.
Conjugation Chemistry
The terminal alkyne functionality facilitates click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), for bioconjugation.
Drug Discovery
Serves as a versatile intermediate in the synthesis of potential pharmaceutical agents. Its functional groups are amenable to diverse derivatisation strategies.
| Molecular weight | 163.60 |
|---|---|
| Empirical formula | C6H9NO2 · HCl |
| Assay | ≥94.5% (TLC)95% |
| Optical activity | [α]/D -12.0±1°, c = 1 in H2O |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3-Amino-5-hexynoic acid hydrochloride primarily used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, for peptide chemistry, drug discovery, and conjugation chemistry due to its amino acid and alkyne functionalities.
What is the CAS number and chemical formula for (R)-3-Amino-5-hexynoic acid hydrochloride?
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The CAS number is 332064-87-6, and the chemical formula is C6H9NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-3-Amino-5-hexynoic acid hydrochloride with a purity of ≥94.5% (TLC) or 95%. This is a research or technical grade material and TSS does not represent it as USP, BP, or EP.
How should (R)-3-Amino-5-hexynoic acid hydrochloride be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid contact with skin and eyes, and ensure good ventilation, as it may cause skin irritation (H315) and serious eye irritation (H319).
Is (R)-3-Amino-5-hexynoic acid hydrochloride controlled or scheduled?
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The provided safety data does not indicate that (R)-3-Amino-5-hexynoic acid hydrochloride is a controlled or scheduled substance.
How is this product typically packed and shipped?
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(R)-3-Amino-5-hexynoic acid hydrochloride is stored at 2-8°C. TSS, as a global supplier and exporter, ensures appropriate packaging and adherence to shipping regulations for fine chemicals.
How can I request a sample or quote for this product?
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Please contact the TSS sales team via our website or directly by phone to request a sample or a quotation for (R)-3-Amino-5-hexynoic acid hydrochloride.
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