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(R)-3-Amino-1,2-propanediol

CAS 66211-46-9C3H9NO2Chemical Synthesis

(R)-3-Amino-1,2-propanediol (CAS 66211-46-9) is a chiral amino alcohol with a molecular weight of 91.11 g/mol. This organic building block is valuable in asymmetric synthesis, serving as a versatile intermediate in complex chemical syntheses. Its stereochemical properties make it particularly useful for constructing enantiomerically pure compounds in research and development settings.

Synonyms
C3H9NO2
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(R)-3-Amino-1,2-propanediol (C3H9NO2) — chemical structure, CAS 66211-46-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Building Block

(R)-3-Amino-1,2-propanediol serves as a crucial chiral synthon in the stereoselective synthesis of complex organic molecules. Its defined stereochemistry is leveraged to introduce specific chirality into target compounds.

Asymmetric Synthesis

This compound is employed in asymmetric synthesis methodologies, enabling the creation of enantiomerically enriched products. It acts as a precursor or auxiliary in reactions requiring precise stereochemical control.

Pharmaceutical Intermediates

As a functionalized chiral molecule, it finds application as an intermediate in the synthesis pathways of various pharmaceutical agents. Its structure facilitates the construction of drug candidates.

Organic Synthesis Reagent

Utilised in general organic synthesis, (R)-3-Amino-1,2-propanediol functions as a versatile reagent for introducing amino and diol functionalities in a stereochemically defined manner.

02 /Properties
Molecular weight91.11
Empirical formulaC3H9NO2
Assay≥98.0% (T)
Optical activity[α]20/D +28±1°, c = 4% in 5 M HCl
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 3259PSN1 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)22-34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
66211-46-9
MDL number
MFCD00798261
Beilstein registry
4290608
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-3-Amino-1,2-propanediol used for?

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(R)-3-Amino-1,2-propanediol is primarily used as a chiral building block and intermediate in asymmetric synthesis, particularly in the development of pharmaceutical agents and other complex organic molecules.

What is the CAS number and formula for (R)-3-Amino-1,2-propanediol?

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The CAS number for (R)-3-Amino-1,2-propanediol is 66211-46-9, and its empirical formula is C3H9NO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-3-Amino-1,2-propanediol with an assay of ≥98.0% (T). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.

How should (R)-3-Amino-1,2-propanediol be handled safely?

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(R)-3-Amino-1,2-propanediol is classified as corrosive and harmful if swallowed. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type N100 or P3), must be used. Handle in a well-ventilated area and avoid contact with skin and eyes.

Is (R)-3-Amino-1,2-propanediol a controlled substance?

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The provided data does not indicate that (R)-3-Amino-1,2-propanediol is a controlled substance.

How is (R)-3-Amino-1,2-propanediol packed and exported?

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This chemical is shipped according to UN 3259, Class 8, Packing Group II regulations. Tech Serve Solutions, established in 1998, is an experienced global supplier and exporter of fine chemicals.

How can I request a sample or quote?

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To request a sample or a quote for (R)-3-Amino-1,2-propanediol, please use the contact form on the Tech Serve Solutions website or contact our sales department directly.

Need (R)-3-Amino-1,2-propanediol in a specific grade or volume?