(R)-3-(Fmoc-amino)-2-methylpropionic acid
(R)-3-(Fmoc-amino)-2-methylpropionic acid (CAS: 211682-15-4), a chiral unnatural amino acid derivative with the formula C19H19NO4 and molecular weight 325.36, is a valuable building block. Its Fmoc protecting group facilitates its use in solid-phase peptide synthesis. It is principally utilised in chemical biology, peptide chemistry, and as a reagent in chemical synthesis, enabling the construction of complex biomolecules and peptidomimetics.
- IUPAC
- (R)-Fmoc-β2-Homoala-OH

Peptide Synthesis
Serves as a non-proteinogenic amino acid building block, incorporating unique structural features and functionalities into peptides through Fmoc-based solid-phase synthesis strategies.
Chemical Biology Research
Enables the creation of modified peptides and peptidomimetics for studying biological processes, protein-protein interactions, and developing novel therapeutic agents.
Chiral Synthesis
A valuable chiral intermediate for the synthesis of complex organic molecules where stereochemical control is essential.
Drug Discovery
Used in the development of novel drug candidates by introducing unnatural amino acid motifs into peptide-based pharmaceuticals, potentially enhancing stability and efficacy.
| Molecular weight | 325.36 |
|---|---|
| Empirical formula | C19H19NO4 |
| Assay | ≥95.0% (HPLC) |
| Optical activity | [α]/D -10.5±1°, c = 1 in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3-(Fmoc-amino)-2-methylpropionic acid used for?
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(R)-3-(Fmoc-amino)-2-methylpropionic acid is primarily used as a building block in peptide synthesis, chemical biology research, chiral synthesis, and drug discovery due to its unnatural amino acid structure and Fmoc protecting group.
What is the CAS number and chemical formula for (R)-3-(Fmoc-amino)-2-methylpropionic acid?
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The CAS number is 211682-15-4 and the chemical formula is C19H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-3-(Fmoc-amino)-2-methylpropionic acid with an assay of ≥95.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should (R)-3-(Fmoc-amino)-2-methylpropionic acid be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if needed. Store at 2-8°C.
Is (R)-3-(Fmoc-amino)-2-methylpropionic acid a hazardous substance?
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This compound is classified under WGK 2 in Germany, indicating it is hazardous to water. Appropriate safety precautions should always be taken during handling and use.
How is this product packed, shipped, and exported?
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Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations for safe transport worldwide.
How can I request a sample or quote for (R)-3-(Fmoc-amino)-2-methylpropionic acid?
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Please contact our sales department via the website or by phone to request a sample or a formal quotation for (R)-3-(Fmoc-amino)-2-methylpropionic acid.
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