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(R)-3-(Boc-amino)pyrrolidine

CAS 122536-77-0C9H18N2O2Chemical Synthesis

(R)-3-(Boc-amino)pyrrolidine (CAS 122536-77-0) is a chiral heterocyclic building block with the molecular formula C9H18N2O2 and a molecular weight of 186.25 g/mol. This tert-butyl carbamate protected pyrrolidine derivative is valuable in asymmetric synthesis and chemical research. Its specific optical activity and protected amine functionality make it a versatile intermediate for complex molecule construction in pharmaceutical and fine chemical development.

IUPAC
tert-Butyl (R)-3-pyrrolidinylcarbamate
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(R)-3-(Boc-amino)pyrrolidine (C9H18N2O2) — chemical structure, CAS 122536-77-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines
01 /Applications

Chiral Building Block in Organic Synthesis

Utilised as a stereochemically defined component in the synthesis of complex organic molecules, particularly in pharmaceutical research and development.

Asymmetric Synthesis Intermediate

Serves as a key intermediate for constructing enantiomerically pure compounds, leveraging its defined stereochemistry.

Heterocyclic Chemistry

Incorporated into synthetic routes requiring the pyrrolidine scaffold, a common motif in many biologically active compounds.

Protecting Group Chemistry

The Boc (tert-butyloxycarbonyl) protecting group allows for selective reactions at other sites before deprotection, facilitating multi-step syntheses.

02 /Properties
Molecular weight186.25
Empirical formulaC9H18N2O2
Assay≥98.0% (TLC)
Optical activity[α]/D +21.5±1.5°, c = 1 in ethanol
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
122536-77-0
MDL number
MFCD00143191
Beilstein registry
5377812
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-3-(Boc-amino)pyrrolidine used for?

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(R)-3-(Boc-amino)pyrrolidine is used as a chiral building block in asymmetric synthesis and chemical research, particularly for constructing complex organic molecules in pharmaceutical and fine chemical development.

What is the CAS number and formula for (R)-3-(Boc-amino)pyrrolidine?

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The CAS number is 122536-77-0 and the empirical formula is C9H18N2O2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-3-(Boc-amino)pyrrolidine with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.

How should (R)-3-(Boc-amino)pyrrolidine be handled safely?

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Based on GHS classification, (R)-3-(Boc-amino)pyrrolidine is a Warning substance classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.

Is (R)-3-(Boc-amino)pyrrolidine a controlled substance?

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The provided data does not indicate that (R)-3-(Boc-amino)pyrrolidine is a controlled substance.

How can I request a sample or quote for (R)-3-(Boc-amino)pyrrolidine?

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To request a sample or quote for (R)-3-(Boc-amino)pyrrolidine, please contact our sales team through the website or by phone, providing the product name and CAS number.

How is (R)-3-(Boc-amino)pyrrolidine typically packed and exported?

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(R)-3-(Boc-amino)pyrrolidine is available from Tech Serve Solutions and can be packed and exported according to customer requirements and international shipping regulations for chemical substances.

Need (R)-3-(Boc-amino)pyrrolidine in a specific grade or volume?