(R)-3-(Boc-amino)pyrrolidine
(R)-3-(Boc-amino)pyrrolidine (CAS 122536-77-0) is a chiral heterocyclic building block with the molecular formula C9H18N2O2 and a molecular weight of 186.25 g/mol. This tert-butyl carbamate protected pyrrolidine derivative is valuable in asymmetric synthesis and chemical research. Its specific optical activity and protected amine functionality make it a versatile intermediate for complex molecule construction in pharmaceutical and fine chemical development.
- IUPAC
- tert-Butyl (R)-3-pyrrolidinylcarbamate

Chiral Building Block in Organic Synthesis
Utilised as a stereochemically defined component in the synthesis of complex organic molecules, particularly in pharmaceutical research and development.
Asymmetric Synthesis Intermediate
Serves as a key intermediate for constructing enantiomerically pure compounds, leveraging its defined stereochemistry.
Heterocyclic Chemistry
Incorporated into synthetic routes requiring the pyrrolidine scaffold, a common motif in many biologically active compounds.
Protecting Group Chemistry
The Boc (tert-butyloxycarbonyl) protecting group allows for selective reactions at other sites before deprotection, facilitating multi-step syntheses.
| Molecular weight | 186.25 |
|---|---|
| Empirical formula | C9H18N2O2 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]/D +21.5±1.5°, c = 1 in ethanol |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3-(Boc-amino)pyrrolidine used for?
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(R)-3-(Boc-amino)pyrrolidine is used as a chiral building block in asymmetric synthesis and chemical research, particularly for constructing complex organic molecules in pharmaceutical and fine chemical development.
What is the CAS number and formula for (R)-3-(Boc-amino)pyrrolidine?
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The CAS number is 122536-77-0 and the empirical formula is C9H18N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-3-(Boc-amino)pyrrolidine with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should (R)-3-(Boc-amino)pyrrolidine be handled safely?
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Based on GHS classification, (R)-3-(Boc-amino)pyrrolidine is a Warning substance classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
Is (R)-3-(Boc-amino)pyrrolidine a controlled substance?
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The provided data does not indicate that (R)-3-(Boc-amino)pyrrolidine is a controlled substance.
How can I request a sample or quote for (R)-3-(Boc-amino)pyrrolidine?
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To request a sample or quote for (R)-3-(Boc-amino)pyrrolidine, please contact our sales team through the website or by phone, providing the product name and CAS number.
How is (R)-3-(Boc-amino)pyrrolidine typically packed and exported?
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(R)-3-(Boc-amino)pyrrolidine is available from Tech Serve Solutions and can be packed and exported according to customer requirements and international shipping regulations for chemical substances.
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