(R)-3-(Boc-amino)-5-hexenoic acid
(R)-3-(Boc-amino)-5-hexenoic acid (CAS: 269726-94-5, C11H19NO4) is a chiral building block featuring a Boc-protected amine and a terminal alkene. With a molecular weight of 229.27 g/mol, this compound is valuable in asymmetric synthesis and peptide chemistry. Its unique structure makes it a versatile intermediate for the construction of complex molecules and unnatural amino acid derivatives in chemical synthesis and chemical biology research.
- IUPAC
- Boc-(R)-3-amino-5-hexenoic acid
- Synonyms
- Boc-(R)-3-amino-5-hexenoic acid

Chiral Synthesis Intermediate
This compound serves as a key chiral building block in the synthesis of complex organic molecules. Its stereochemistry is critical for introducing specific configurations in target compounds.
Peptide Chemistry
As a derivative of an amino acid, it is utilized in peptide synthesis, particularly for incorporating unnatural amino acids to modify peptide properties or create novel peptide structures.
Asymmetric Synthesis
The enantiomeric purity of (R)-3-(Boc-amino)-5-hexenoic acid makes it suitable for asymmetric synthesis, enabling the creation of stereospecific products.
Organic Building Block
Its functional groups, including the alkene and protected amine, allow for diverse chemical transformations, making it a versatile reagent in organic synthesis.
| Molecular weight | 229.27 |
|---|---|
| Empirical formula | C11H19NO4 |
| Assay | ≥97.5% (HPLC)98% |
| Optical activity | [α]/D -20.0±1°, c = 1 in ethanol |
| Optical purity | enantiomeric excess: ≥99.0% |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3-(Boc-amino)-5-hexenoic acid used for?
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(R)-3-(Boc-amino)-5-hexenoic acid is primarily used as a chiral building block in organic synthesis, particularly in asymmetric synthesis and peptide chemistry for creating complex molecules and unnatural amino acid derivatives.
What is the CAS number and molecular formula?
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The CAS number is 269726-94-5, and the molecular formula is C11H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-3-(Boc-amino)-5-hexenoic acid with an assay of ≥97.5% (HPLC) and 98%, and an enantiomeric excess of ≥99.0%. This product is not supplied as USP, BP, or EP grade.
How should (R)-3-(Boc-amino)-5-hexenoic acid be handled safely?
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This compound is a Warning chemical with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, should be worn. Ensure good ventilation and avoid dust formation.
How is (R)-3-(Boc-amino)-5-hexenoic acid packed and shipped?
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This product is stored at 2-8°C. For specific packing and shipping information for export, please contact Tech Serve Solutions directly.
How can I request a sample or quote?
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You can request a sample or a quote for (R)-3-(Boc-amino)-5-hexenoic acid by contacting our sales department via the website or by telephone.
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