(R)-3-(Boc-amino)-2-phenylpropionic acid
(R)-3-(Boc-amino)-2-phenylpropionic acid (CAS: 181140-88-5), with the molecular formula C14H19NO4 and a molecular weight of 265.30 g/mol, is a protected beta-amino acid. It serves as a valuable chiral building block in organic synthesis, particularly in the development of novel pharmaceutical compounds and in peptide chemistry. Its structure incorporates a Boc-protected amine and a phenyl group, making it useful for introducing specific functionalities into target molecules.
- IUPAC
- (R)-Boc-2-phenyl-β-alanine
- Synonyms
- (R)-Boc-2-phenyl-β-alanine
Chiral Building Block in Organic Synthesis
This compound is utilised as a key chiral intermediate for constructing complex organic molecules. Its defined stereochemistry at the alpha-carbon allows for enantioselective synthesis of target compounds.
Peptide Chemistry
As a protected beta-amino acid derivative, it finds application in the synthesis of unnatural peptides and peptidomimetics. The Boc protection facilitates controlled coupling reactions in solid-phase or solution-phase peptide synthesis.
Pharmaceutical Intermediate
It acts as a precursor in the synthesis of various pharmaceutical agents and drug candidates. Its incorporation can lead to molecules with improved pharmacokinetic or pharmacodynamic properties.
Research and Development
This compound is employed in academic and industrial research settings for exploring new synthetic routes and developing novel chemical entities.
| Molecular weight | 265.30 |
|---|---|
| Empirical formula | C14H19NO4 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]/D +45.5±1.5°, c = 1 in DMF |
| Composition | carbon, 62.6-64.2%nitrogen, 4.8-5.7% |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3-(Boc-amino)-2-phenylpropionic acid used for?
+
(R)-3-(Boc-amino)-2-phenylpropionic acid is primarily used as a chiral building block in organic synthesis, particularly in peptide chemistry and as an intermediate for pharmaceutical development.
What are the CAS number and molecular formula of this compound?
+
The CAS number is 181140-88-5 and the molecular formula is C14H19NO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound with a purity of ≥98.0% by HPLC. We do not represent this product as USP, BP, or EP grade.
How should (R)-3-(Boc-amino)-2-phenylpropionic acid be handled safely?
+
This compound is classified as a Warning under GHS. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves should be used. Handle in a well-ventilated area and avoid dust formation.
Is this chemical available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped internationally.
How can I request a sample or quote?
+
To request a sample or obtain a quote, please contact our sales department through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis