(R)-3,3′-Di-tert-butyl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-(bi-2-naphthol) dipotassium salt
(R)-3,3′-Di-tert-butyl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-(bi-2-naphthol) dipotassium salt (CAS 350683-75-9) is a BINOL derivative with the molecular formula C28H36K2O2. This octahydro-BINOL compound serves as a valuable chiral ligand in asymmetric synthesis. It has been demonstrated as an effective ligand in molybdenum-catalysed desymmetrisation reactions, particularly in asymmetric ring-closing metathesis, facilitating the creation of enantiomerically enriched products.
- Synonyms
- 6,6′,7,7′,8,8′-octahydro-1,1′-(bi-2-naphthol) dipotassium salt350683-75-9C28H36K2O2
Asymmetric Synthesis Ligand
This octahydro-BINOL derivative functions as a crucial chiral ligand in transition metal-catalysed asymmetric transformations. Its specific structure enables high enantioselectivity in key synthetic steps.
Molybdenum-Catalysed Reactions
The compound has been specifically cited for its efficacy as a ligand in Mo-catalysed desymmetrisation of trienes. This application is significant in the stereoselective synthesis of complex molecules.
Ring-Closing Metathesis
Its use in asymmetric ring-closing metathesis contributes to the stereocontrolled formation of cyclic structures, a fundamental process in organic chemistry and drug discovery.
| Molecular weight | 482.78 |
|---|---|
| Empirical formula | C28H36K2O2 |
| Assay | ≥95.0% (dry substance, CHN) |
| Impurities tested | <10% water |
| Application | Octahydro-BINOL was demonstrated to be an effective ligand in Mo-catalyzed desymmetrization of a triene by asymmetric ring closing metathesis.1,2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3,3′-Di-tert-butyl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-(bi-2-naphthol) dipotassium salt used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis, notably in molybdenum-catalysed desymmetrisation reactions involving trienes and in asymmetric ring-closing metathesis.
What are the CAS number and formula for this BINOL derivative?
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The CAS number is 350683-75-9 and the molecular formula is C28H36K2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥95.0% (dry substance, CHN). It contains <10% water. We do not represent this product as USP/BP/EP or other pharmacopoeia grades.
What are the safety considerations when handling this chemical?
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Appropriate personal protective equipment, including eyeshields and gloves, is essential. A type N95 (US) or P1 (EN143) respirator filter should be used. The substance has a WGK (Germany) classification of 3, indicating it is hazardous to water.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team directly via our website or by telephone to request a quotation or inquire about obtaining a sample.
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