Z-Ile-Bt
Z-Ile-Bt (CAS: 1072442-07-9), a derivative of isoleucine with the molecular formula C20H22N4O3 and a molecular weight of 366.41 g/mol, functions as a key benzotriazole amino acid reagent. It is instrumental in the chemical synthesis of peptides, peptidomimetics, and various conjugates. Its utility spans chemical biology and advanced peptide chemistry applications, offering a reliable building block for complex molecular structures.
- IUPAC
- (1S,2S-N-Z-1-Benzotriazolylcarbonyl-2-methylbutylamine,Benzyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate
Peptide Synthesis
Utilised in the preparation of standard polypeptides and their derivatives. Z-Ile-Bt serves as a versatile reagent for forming amide bonds critical in peptide chain elongation.
Peptidomimetic Development
Facilitates the synthesis of structurally diverse peptidomimetics, including aminoxypeptides, depsipeptides, and heterocyclic analogues. These compounds are valuable in drug discovery and biochemical research.
Conjugate Chemistry
Enables the formation of peptide conjugates through N, O, S, and C linkages. This allows for the attachment of peptides to other molecules, such as fluorescent labels or various functional groups.
Chemical Biology Tools
Serves as a building block for creating specialised molecules used in chemical biology investigations. Its structure supports the development of tagged peptides and other biologically relevant probes.
| Molecular weight | 366.41 |
|---|---|
| Empirical formula | C20H22N4O3 |
| Assay | 95% |
| Storage temperature | −20°C |
| Application | Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:• Polypeptidal benzotriazolides1• Peptidomimetics, such as aminoxypeptides2, depsipeptides3 and heterocyclic peptidomimetics4• Tagged peptides and peptidomimetics, particularly those with fluorescent labels5,6• N, O, S, and C linked peptide conjugates6 |
| Melting point | 77-82 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Ile-Bt used for?
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Z-Ile-Bt is primarily used in the synthesis of peptides, peptidomimetics, and various conjugates. It is a key reagent in chemical biology and peptide chemistry.
What is the CAS number and formula for Z-Ile-Bt?
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The CAS number for Z-Ile-Bt is 1072442-07-9, and its empirical formula is C20H22N4O3.
What grade and purity does Tech Serve Solutions supply for Z-Ile-Bt?
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Tech Serve Solutions supplies Z-Ile-Bt with an assay of 95%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the safety considerations when handling Z-Ile-Bt?
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Z-Ile-Bt is classified under WGK Germany 3, indicating a higher hazard level. Handling should be performed with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling and storage instructions.
How is Z-Ile-Bt stored and shipped?
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Z-Ile-Bt should be stored at -20°C. Tech Serve Solutions exports chemicals globally, adhering to all necessary shipping regulations for chemical compounds.
How can I request a sample or quote for Z-Ile-Bt?
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To request a sample or a quotation for Z-Ile-Bt, please contact our sales team through the TSS website or by direct inquiry, providing your specific requirements.
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