Z-Homophe-OH
Z-Homophe-OH (CAS: 127862-89-9; C18H19NO4) is a non-proteinogenic amino acid derivative. This compound, identified by its molecular weight of 313.35 g/mol, serves as a valuable building block in chemical synthesis. It finds primary application in the fields of chemical biology and peptide chemistry, particularly for the incorporation of unnatural amino acid structures into peptides and related molecules.
- IUPAC
- (S)-2-(Z-amino)-4-phenylbutyric acid,Z-L-homophenylalanine
- Synonyms
- (S)-2-(Z-amino)-4-phenylbutyric acidZ-L-homophenylalanine

Chemical Biology Research
Z-Homophe-OH is employed in chemical biology to synthesise modified peptides or proteins. Its incorporation can alter the structural or functional properties of biomolecules for research purposes.
Peptide Synthesis
As a homo-amino acid derivative, it is utilised in solid-phase or solution-phase peptide synthesis. It enables the creation of peptidomimetics and peptides with enhanced stability or altered biological activity.
Organic Synthesis Intermediate
The compound serves as a versatile intermediate in organic synthesis. Its unique structure allows for further chemical modifications to produce complex molecules for various research applications.
Unnatural Amino Acid Derivatives
It is a key component in the synthesis of unnatural amino acid derivatives, expanding the toolkit for medicinal chemistry and drug discovery programmes.
| Molecular weight | 313.35 |
|---|---|
| Empirical formula | C18H19NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Homophe-OH primarily used for?
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Z-Homophe-OH is primarily used as a building block in chemical synthesis, particularly in chemical biology and peptide chemistry, to create unnatural amino acid derivatives and modified peptides.
What are the CAS number and molecular formula for Z-Homophe-OH?
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The CAS number for Z-Homophe-OH is 127862-89-9, and its molecular formula is C18H19NO4.
What grade and purity does Tech Serve Solutions supply for Z-Homophe-OH?
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Tech Serve Solutions supplies Z-Homophe-OH with an assay of ≥98.0% determined by TLC. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Z-Homophe-OH be handled safely?
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When handling Z-Homophe-OH, it is recommended to use safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary, as indicated by its safety data.
Is Z-Homophe-OH available for export by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Z-Homophe-OH, catering to international research and industrial needs.
How can I request a sample or quote for Z-Homophe-OH?
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To request a sample or a quotation for Z-Homophe-OH, please contact our sales department through the website or by phone, providing your specific requirements.
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