Z-His-OH
Nα-Carbobenzyloxy-L-histidine (CAS: 14997-58-1) is a protected amino acid derivative with the molecular formula C14H15N3O4. This compound serves as a crucial building block in peptide synthesis and chemical biology research. Its protected nature allows for controlled reactions, making it indispensable for constructing complex peptide sequences and developing novel chemical entities. TSS supplies this high-purity reagent for demanding scientific applications.
- IUPAC
- Nα-Carbobenzyloxy-L-histidine,Nα-Z-L-Histidine
- Synonyms
- Nα-Carbobenzyloxy-L-histidineNα-Z-L-Histidine
Peptide Synthesis
Nα-Carbobenzyloxy-L-histidine is extensively used as a protected amino acid in solid-phase and solution-phase peptide synthesis. The carbobenzyloxy (Z) group provides robust protection for the alpha-amino group, enabling selective coupling reactions during peptide chain elongation.
Chemical Biology
This histidine derivative is employed in chemical biology to incorporate modified or unnatural histidine residues into peptides and proteins. This allows for the study of protein function, enzyme mechanisms, and the development of peptide-based therapeutics.
Organic Synthesis
As a versatile intermediate, Nα-Carbobenzyloxy-L-histidine is utilised in the synthesis of various complex organic molecules and biologically active compounds. Its distinct functional groups can be selectively manipulated for targeted chemical transformations.
| Molecular weight | 289.29 |
|---|---|
| Empirical formula | C14H15N3O4 |
| Assay | 99% |
| Optical activity | [α]20/D −24°, c = 1% in 6 M HCl |
| Melting point | 168 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Carbobenzyloxy-L-histidine used for?
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Nα-Carbobenzyloxy-L-histidine is primarily used in peptide synthesis and chemical biology research as a protected amino acid building block for creating complex peptide structures and modified biomolecules.
What is the CAS number and molecular formula of Nα-Carbobenzyloxy-L-histidine?
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The CAS number is 14997-58-1, and the molecular formula is C14H15N3O4.
What grade and purity does Tech Serve Solutions supply for Nα-Carbobenzyloxy-L-histidine?
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Tech Serve Solutions supplies Nα-Carbobenzyloxy-L-histidine with an assay of 99%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for Nα-Carbobenzyloxy-L-histidine?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if dust is generated. This compound is classified with WGK 3 in Germany, indicating it is hazardous.
How is Nα-Carbobenzyloxy-L-histidine shipped and exported?
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Tech Serve Solutions specialises in global supply and export of fine chemicals, adhering to all necessary regulations for safe and compliant international shipping. Specific shipping details will be provided upon inquiry.
How can I request a sample or quote for Nα-Carbobenzyloxy-L-histidine?
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To request a sample or a quotation, please contact our sales team via the website or by phone. Please specify the product name and CAS number (14997-58-1) in your request.
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