2-Chloro-4,5-difluorobenzonitrile
2-Chloro-4,5-difluorobenzonitrile (CAS: 135748-34-4) is a fluorinated aromatic compound with the molecular formula C7H2ClF2N and a molecular weight of 173.55 g/mol. This nitrile serves as a key building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its specific substitution pattern makes it a valuable intermediate for introducing fluorinated aryl moieties into complex molecules. Available from Tech Serve Solutions with a purity of 97%.
- Synonyms
- C7H2ClF2N2-Chloro-4,5-difluorobenzonitrile
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the introduction of a chloro-difluorobenzonitrile fragment is required. This can contribute to enhanced metabolic stability or receptor binding affinity in drug candidates.
Agrochemical Synthesis
Serves as a precursor in the development of novel pesticides and herbicides. The fluorinated aromatic structure can impart specific biological activities and environmental persistence profiles to agrochemical products.
Material Science
Explored as a component in the synthesis of advanced materials. The unique electronic properties conferred by the fluorine and nitrile groups can be advantageous in polymers or specialised organic electronic applications.
Organic Synthesis Building Block
A versatile reagent for general organic synthesis, enabling access to a range of substituted benzonitriles and related compounds. Its reactivity allows for further functionalization and elaboration into more complex molecular architectures.
| Molecular weight | 173.55 |
|---|---|
| Empirical formula | C7H2ClF2N |
| Assay | 97% |
| Melting point | 35-40 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4,5-difluorobenzonitrile used for?
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2-Chloro-4,5-difluorobenzonitrile is primarily used as a building block in organic synthesis, particularly for pharmaceuticals, agrochemicals, and advanced materials. Its specific structure allows for the introduction of fluorinated aromatic moieties into target molecules.
What is the CAS number and molecular formula for 2-Chloro-4,5-difluorobenzonitrile?
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The CAS number is 135748-34-4 and the molecular formula is C7H2ClF2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4,5-difluorobenzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-4,5-difluorobenzonitrile be handled?
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This compound is harmful if swallowed, in contact with skin, or if inhaled (H302 + H312 + H332). It also causes skin irritation (H315) and serious eye irritation (H319). Always wear appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, and handle in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling information.
How is 2-Chloro-4,5-difluorobenzonitrile shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of chemicals. We handle the shipping and export of 2-Chloro-4,5-difluorobenzonitrile in compliance with all relevant international regulations. UN 2811, 6.1, PGIII designation applies.
How can I request a sample or a quote?
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Please contact our sales team through the website or via email to request a sample or obtain a quotation for 2-Chloro-4,5-difluorobenzonitrile.
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