2-Chloro-4,6-difluoroaniline
2-Chloro-4,6-difluoroaniline (CAS: 36556-56-6), with the molecular formula C6H4ClF2N and a molecular weight of 163.55, is a fluorinated aromatic amine. It serves as a valuable building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. Its specific substitution pattern makes it a useful intermediate for introducing difluoroaniline moieties into more complex molecular structures, facilitating research and development in chemical synthesis.
- Synonyms
- C6H4ClF2N2-Chloro-4,6-difluorobenzeneamine

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), where the difluoroaniline structure can impart desirable pharmacokinetic properties.
Agrochemical Development
Serves as a key intermediate in the creation of novel pesticides and herbicides, contributing to the development of advanced crop protection solutions.
Organic Synthesis Building Block
A versatile reagent for introducing chlorinated and fluorinated aromatic amine functionalities into diverse organic molecules.
Materials Science
Potential applications in the development of specialised polymers and functional materials where its unique electronic and structural properties can be exploited.
| Molecular weight | 163.55 |
|---|---|
| Empirical formula | C6H4ClF2N |
| Assay | 97% |
| Melting point | 28-32 °C(lit.) |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-38-41 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4,6-difluoroaniline used for?
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2-Chloro-4,6-difluoroaniline is primarily used as a building block in organic synthesis, with significant applications in the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 2-Chloro-4,6-difluoroaniline?
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The CAS number is 36556-56-6 and the empirical formula (Hill notation) is C6H4ClF2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4,6-difluoroaniline with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 2-Chloro-4,6-difluoroaniline?
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This compound is classified as Danger, with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), and H318 (Causes serious eye damage). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a type P2 respirator, must be used. Handle with extreme caution.
How is 2-Chloro-4,6-difluoroaniline packed, shipped, and exported?
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2-Chloro-4,6-difluoroaniline is packed and shipped according to international regulations for hazardous materials. Tech Serve Solutions has extensive experience in exporting chemicals globally.
How can I request a sample or quote for 2-Chloro-4,6-difluoroaniline?
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To request a sample or quote, please contact our sales department through the website or by phone, providing your specific requirements.
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