Fmoc-D-Pro-OH
Fmoc-D-Pro-OH (CAS: 101555-62-8), with the molecular formula C20H19NO4 and a molecular weight of 337.37 g/mol, is a protected amino acid derivative. It is utilized in peptide synthesis and chemical biology research. This compound is a key building block for creating peptides with specific D-amino acid sequences, offering unique structural and functional properties compared to their L-amino acid counterparts. Its N-terminal Fmoc protection facilitates controlled peptide chain elongation.
- IUPAC
- Fmoc-D-proline
Peptide Synthesis
Fmoc-D-Pro-OH is used as a crucial building block in solid-phase peptide synthesis (SPPS) employing Fmoc chemistry. It enables the incorporation of D-proline residues into peptide chains, influencing secondary structures and biological activity.
Chemical Biology
This derivative serves as a reagent in chemical biology for constructing peptides with non-natural amino acids. These modified peptides can be used to study protein-protein interactions, enzyme mechanisms, and develop novel therapeutic agents.
Organic Synthesis
As a chiral building block, Fmoc-D-Pro-OH is applicable in various organic synthesis strategies. Its defined stereochemistry makes it valuable for constructing complex chiral molecules and natural products.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C20H19NO4 |
| Assay | ≥98.0% |
| Optical activity | [α]/D +31.0±3.0°, c = 1 in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Pro-OH used for?
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Fmoc-D-Pro-OH is primarily used as a building block in peptide synthesis, particularly in solid-phase peptide synthesis utilizing Fmoc chemistry, and in broader chemical biology research for creating peptides with specific D-amino acid sequences.
What are the CAS number and formula for Fmoc-D-Pro-OH?
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The CAS number for Fmoc-D-Pro-OH is 101555-62-8, and its empirical formula is C20H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Pro-OH with an assay of ≥98.0%. This product is typically considered a research or technical grade chemical. Tech Serve Solutions does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-D-Pro-OH be handled and stored?
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Fmoc-D-Pro-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended. Store the chemical at 2-8°C to maintain its integrity.
Is Fmoc-D-Pro-OH a controlled substance?
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Based on the provided data, there is no indication that Fmoc-D-Pro-OH is a controlled substance.
How is Fmoc-D-Pro-OH packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing for chemical stability and safe transit. Specific packing details can be provided upon request for export orders.
How can I request a sample or quote for Fmoc-D-Pro-OH?
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To request a sample or a quotation for Fmoc-D-Pro-OH, please contact our sales department through the official Tech Serve Solutions website or by phone.
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