Fmoc-D-Phe(4-NO2)-OH
Fmoc-D-Phe(4-NO2)-OH (CAS: 177966-63-1), with the molecular formula C24H20N2O6, is a specialised unnatural amino acid derivative. It features a D-phenylalanine core modified with a nitro group at the para position and protected with the Fmoc group. This compound is valuable in peptide chemistry for incorporating non-proteinogenic amino acids into peptide sequences, aiding in the study of structure-activity relationships and the development of novel peptides.
- IUPAC
- Fmoc-4-nitro-D-phenylalanine

Peptide Synthesis
Used as a building block in solid-phase and solution-phase peptide synthesis to introduce Fmoc-protected 4-nitro-D-phenylalanine. It enables the creation of peptides with modified side chains for research purposes.
Chemical Biology Research
Facilitates the design and synthesis of peptides and peptidomimetics for studying protein interactions, enzyme inhibition, and developing biochemical probes.
Drug Discovery and Development
Incorporation into peptide-based drug candidates to explore structure-activity relationships and enhance metabolic stability or receptor binding.
Material Science
Exploration in the development of novel biomaterials and functionalised surfaces through peptide self-assembly.
| Molecular weight | 432.43 |
|---|---|
| Empirical formula | C24H20N2O6 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe(4-NO2)-OH used for?
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Fmoc-D-Phe(4-NO2)-OH is primarily used as a specialised building block in peptide synthesis, particularly for introducing the unnatural amino acid 4-nitro-D-phenylalanine into peptide chains. It is valuable in chemical biology and drug discovery research for creating modified peptides.
What are the CAS number and formula for Fmoc-D-Phe(4-NO2)-OH?
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The CAS number for Fmoc-D-Phe(4-NO2)-OH is 177966-63-1, and its empirical formula is C24H20N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phe(4-NO2)-OH with an assay of ≥98.0% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-D-Phe(4-NO2)-OH be handled and stored?
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According to the safety data, this compound has a WGK Germany rating of 3, indicating it is hazardous to water. It should be stored at refrigeration temperatures between 2-8°C. Handle with appropriate personal protective equipment to avoid exposure.
How is Fmoc-D-Phe(4-NO2)-OH packed, shipped, and exported?
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Fmoc-D-Phe(4-NO2)-OH is carefully packed to maintain its integrity during transit. Tech Serve Solutions is a global supplier and exporter, equipped to handle international shipments of fine chemicals.
How can I request a sample or quote for Fmoc-D-Phe(4-NO2)-OH?
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To request a sample or a quotation for Fmoc-D-Phe(4-NO2)-OH, please use the contact form on our website or reach out to our sales department directly. Please specify the required quantity and your shipping details.
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