Fmoc-D-Phe(4-Cl)-OH
Fmoc-D-Phe(4-Cl)-OH (CAS 142994-19-2), with a molecular weight of 421.87 g/mol, is a protected unnatural amino acid derivative. It is a key building block in peptide synthesis, particularly for creating peptides with modified or non-natural structures. This compound is widely utilised in chemical biology and organic synthesis research due to its specific structure and reactivity.
- IUPAC
- Fmoc-4-chloro-D-phenylalanine
- Synonyms
- Fmoc-4-chloro-D-phenylalanine
Peptide Synthesis
Fmoc-D-Phe(4-Cl)-OH serves as a crucial building block in solid-phase and solution-phase peptide synthesis. It allows for the incorporation of a chlorinated phenylalanine analogue into peptide chains, enabling the study of structure-activity relationships.
Chemical Biology Research
Researchers use this derivative to explore the effects of halogenated amino acids on peptide structure, function, and biological interactions. It is valuable for designing peptides with altered pharmacokinetic properties or specific binding affinities.
Organic Synthesis
As a specialised reagent, Fmoc-D-Phe(4-Cl)-OH is employed in complex organic synthesis pathways. Its protected nature facilitates controlled reactions and the construction of novel molecules with potential pharmaceutical applications.
| Molecular weight | 421.87 |
|---|---|
| Empirical formula | C24H20ClNO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe(4-Cl)-OH used for?
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Fmoc-D-Phe(4-Cl)-OH is primarily used as a protected building block in peptide synthesis, chemical biology research, and organic synthesis for creating peptides containing a chlorinated phenylalanine analogue.
What are the CAS number and formula for Fmoc-D-Phe(4-Cl)-OH?
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The CAS number for Fmoc-D-Phe(4-Cl)-OH is 142994-19-2 and its empirical formula is C24H20ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phe(4-Cl)-OH with a purity of ≥98.0% by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-D-Phe(4-Cl)-OH be handled safely?
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Handle Fmoc-D-Phe(4-Cl)-OH with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. This compound is a warning-hazardous substance, causing skin and eye irritation and potentially respiratory irritation.
Is Fmoc-D-Phe(4-Cl)-OH exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Fmoc-D-Phe(4-Cl)-OH.
How can I request a sample or quote for Fmoc-D-Phe(4-Cl)-OH?
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To request a sample or quote, please contact our sales team through the provided channels on the Tech Serve Solutions website, referencing the product name and CAS number 142994-19-2.
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